A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation

A new, practical, three-component method for the synthesis of 5-aza-9-deaza-adenines is developed. Aminopyrazoles react in a one-pot fashion with triethyl orthoformate and cyanamide under microwave irradiation affording 5-aza-9-deaza-adenines in good yields and high purity. The main advantages of th...

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Main Authors: Lim, Felicia Phei Lin, Luna, Giuseppe, Dolzhenko, Anton
Format: Journal Article
Published: Pergamon 2014
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/44673
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author Lim, Felicia Phei Lin
Luna, Giuseppe
Dolzhenko, Anton
author_facet Lim, Felicia Phei Lin
Luna, Giuseppe
Dolzhenko, Anton
author_sort Lim, Felicia Phei Lin
building Curtin Institutional Repository
collection Online Access
description A new, practical, three-component method for the synthesis of 5-aza-9-deaza-adenines is developed. Aminopyrazoles react in a one-pot fashion with triethyl orthoformate and cyanamide under microwave irradiation affording 5-aza-9-deaza-adenines in good yields and high purity. The main advantages of this method are the operational simplicity, accessibility and high efficiency
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format Journal Article
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institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T09:22:14Z
publishDate 2014
publisher Pergamon
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spelling curtin-20.500.11937-446732017-09-13T14:13:04Z A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation Lim, Felicia Phei Lin Luna, Giuseppe Dolzhenko, Anton Cyanamide Multicomponent reaction Triazine Pyrazole Purine analogue A new, practical, three-component method for the synthesis of 5-aza-9-deaza-adenines is developed. Aminopyrazoles react in a one-pot fashion with triethyl orthoformate and cyanamide under microwave irradiation affording 5-aza-9-deaza-adenines in good yields and high purity. The main advantages of this method are the operational simplicity, accessibility and high efficiency 2014 Journal Article http://hdl.handle.net/20.500.11937/44673 10.1016/j.tetlet.2014.07.105 Pergamon restricted
spellingShingle Cyanamide
Multicomponent reaction
Triazine
Pyrazole
Purine analogue
Lim, Felicia Phei Lin
Luna, Giuseppe
Dolzhenko, Anton
A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation
title A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation
title_full A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation
title_fullStr A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation
title_full_unstemmed A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation
title_short A new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation
title_sort new, one-pot, multicomponent synthesis of 5-aza-9-deaza-adenines under microwave irradiation
topic Cyanamide
Multicomponent reaction
Triazine
Pyrazole
Purine analogue
url http://hdl.handle.net/20.500.11937/44673