Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice

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Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice

Changes to innate cells, such as macrophages and myeloid-derived suppressor cells (MDSCs), during aging in healthy or tumor-bearing hosts are not well understood. We compared macrophage subpopulations and MDSCs from healthy young (6–8 weeks) C57BL/6J mice to those from healthy geriatric (24–28 month...

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Bibliographic Details
Main Authors:	Jackaman, Connie, Radley-Crabb, Hannah, Soffe, Z., Shavlakadze, T., Grounds, M., Nelson, Delia
Format:	Journal Article
Published:	Wiley-Blackwell 2013
Subjects:	interleukin-2 cancer immunotherapy macrophage CD40 aging
Online Access:	http://hdl.handle.net/20.500.11937/44664

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