Targeting p110gamma in gastrointestinal cancers: attack on multiple fronts

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Targeting p110gamma in gastrointestinal cancers: attack on multiple fronts

Phosphoinositide 3-kinases (PI3Ks) regulate several cellular functions that are critical for cancer progression and development, including cell survival, proliferation and migration. Three classes of PI3Ks exist with the class I PI3K encompassing four isoforms of the catalytic subunit known as p110α...

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Bibliographic Details
Main Authors:	Falasca, Marco, Maffucci, T.
Format:	Journal Article
Published:	Frontiers Media SA 2014
Subjects:	391 inflammation phosphoinositide3-kinase metastasis PDAC angiogenesis cancer HCC
Online Access:	http://hdl.handle.net/20.500.11937/44574

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