Sitting time, physical activity and cervical intraepithelial neoplasia in Australian women: A preliminary investigation

Issue addressed: Physical activity affects the immune system, which in turn may modify the risk of cervical intraepithelial neoplasia (CIN). The effect of sitting on CIN is unknown. This study investigated the relationship between sitting time, physical activity and the risk of CIN. Methods: Communi...

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Main Authors: Chih, Hui Jun, Lee, Andy, Colville, Linda, Xu, D., Binns, Colin
Format: Journal Article
Published: Australian Health Promotion Association 2013
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/44354
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author Chih, Hui Jun
Lee, Andy
Colville, Linda
Xu, D.
Binns, Colin
author_facet Chih, Hui Jun
Lee, Andy
Colville, Linda
Xu, D.
Binns, Colin
author_sort Chih, Hui Jun
building Curtin Institutional Repository
collection Online Access
description Issue addressed: Physical activity affects the immune system, which in turn may modify the risk of cervical intraepithelial neoplasia (CIN). The effect of sitting on CIN is unknown. This study investigated the relationship between sitting time, physical activity and the risk of CIN. Methods: Community-dwelling adult women within metropolitan Perth, Western Australia, who had had a Papanicolaou (Pap) smear test at any of five clinics and medical centres, were approached by their general practitioners. In total, 348 women were recruited and interviewed for information on sitting time, physical activity level and lifetime physical activity exposure using the International Physical Activity Questionnaire (IPAQ) – short form. Associations of exposure variables with CIN risk were assessed by unconditional logistic regression analyses. Results: The prevalence of abnormal Pap smear status indicating CIN was found to be 15.8%. Women with prolonged sitting duration (≥ 42 h per week) had significantly increased risk of CIN (adjusted OR 3.49, 95% CI 1.12–10.88) than women who sat less than 24.5 h per week. Although the effect of total physical activity level was non-significant (P = 0.408), being always involved in physical activity during the entire life appeared to be inversely associated with the CIN risk (P = 0.036). Conclusions: Prolonged sitting time was significantly associated with increased risk of abnormal Pap smear status indicating CIN. So what?: This preliminary investigation highlights a new prospect for health-promotion intervention to reduce the risk of CIN. Health practitioners should encourage women to reduce their sitting time and maintain physically active throughout their life course.
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spelling curtin-20.500.11937-443542019-05-28T08:39:11Z Sitting time, physical activity and cervical intraepithelial neoplasia in Australian women: A preliminary investigation Chih, Hui Jun Lee, Andy Colville, Linda Xu, D. Binns, Colin sedentary prolonged sitting Issue addressed: Physical activity affects the immune system, which in turn may modify the risk of cervical intraepithelial neoplasia (CIN). The effect of sitting on CIN is unknown. This study investigated the relationship between sitting time, physical activity and the risk of CIN. Methods: Community-dwelling adult women within metropolitan Perth, Western Australia, who had had a Papanicolaou (Pap) smear test at any of five clinics and medical centres, were approached by their general practitioners. In total, 348 women were recruited and interviewed for information on sitting time, physical activity level and lifetime physical activity exposure using the International Physical Activity Questionnaire (IPAQ) – short form. Associations of exposure variables with CIN risk were assessed by unconditional logistic regression analyses. Results: The prevalence of abnormal Pap smear status indicating CIN was found to be 15.8%. Women with prolonged sitting duration (≥ 42 h per week) had significantly increased risk of CIN (adjusted OR 3.49, 95% CI 1.12–10.88) than women who sat less than 24.5 h per week. Although the effect of total physical activity level was non-significant (P = 0.408), being always involved in physical activity during the entire life appeared to be inversely associated with the CIN risk (P = 0.036). Conclusions: Prolonged sitting time was significantly associated with increased risk of abnormal Pap smear status indicating CIN. So what?: This preliminary investigation highlights a new prospect for health-promotion intervention to reduce the risk of CIN. Health practitioners should encourage women to reduce their sitting time and maintain physically active throughout their life course. 2013 Journal Article http://hdl.handle.net/20.500.11937/44354 10.1071/HE13073 Australian Health Promotion Association fulltext
spellingShingle sedentary
prolonged sitting
Chih, Hui Jun
Lee, Andy
Colville, Linda
Xu, D.
Binns, Colin
Sitting time, physical activity and cervical intraepithelial neoplasia in Australian women: A preliminary investigation
title Sitting time, physical activity and cervical intraepithelial neoplasia in Australian women: A preliminary investigation
title_full Sitting time, physical activity and cervical intraepithelial neoplasia in Australian women: A preliminary investigation
title_fullStr Sitting time, physical activity and cervical intraepithelial neoplasia in Australian women: A preliminary investigation
title_full_unstemmed Sitting time, physical activity and cervical intraepithelial neoplasia in Australian women: A preliminary investigation
title_short Sitting time, physical activity and cervical intraepithelial neoplasia in Australian women: A preliminary investigation
title_sort sitting time, physical activity and cervical intraepithelial neoplasia in australian women: a preliminary investigation
topic sedentary
prolonged sitting
url http://hdl.handle.net/20.500.11937/44354