Synthesis and antimalarial evaluation of novel isocryptolepine derivatives
A series of mono- and di-substituted analogues of isocryptolepine have been synthesized and evaluated for in vitro antimalarial activity against chloroquine sensitive (3D7) and resistant (W2mef) Plasmodium falciparum and for cytotoxicity (3T3 cells). Di-halogenated compounds were the most potent der...
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Bibliographic Details
| Main Authors: |
Whittell, Louise,
Batty, Kevin,
Wong, R.,
Bolitho, Erin,
Fox, Simon,
Davis, T.,
Murray, Paul |
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| Format: | Journal Article
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| Published: |
Elsevier
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/44272
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