Genetic and epigenetic regulation of phosphoinositide 3-kinase isoforms
The last quarter of a century has witnessed remarkable progress in the understanding of phosphoinositide 3-kinases (PI3K) signalling and their involvement in different diseases such as cancer, diabetes and inflammation. Nevertheless, many questions remain open and among these the role of genetic and...
| Main Authors: | , , |
|---|---|
| Format: | Journal Article |
| Published: |
2013
|
| Online Access: | http://hdl.handle.net/20.500.11937/44263 |
Similar Items
3-phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer
by: Fyffe, C., et al.
Published: (2013)
by: Fyffe, C., et al.
Published: (2013)
THE CLASS II PHOSPHOINOSITIDE 3-KINASE ISOFORM beta REGULATES PLATELET FUNCTION AND ARTERIAL THROMBOSIS IN MICE
by: Tibolla, G., et al.
Published: (2011)
by: Tibolla, G., et al.
Published: (2011)
Regulation and cellular functions of class II phosphoinositide 3-kinases
by: Falasca, Marco, et al.
Published: (2012)
by: Falasca, Marco, et al.
Published: (2012)
Targeting phosphoinositide 3-kinase pathways in pancreatic cancer - from molecular signalling to clinical trials
by: Falasca, Marco, et al.
Published: (2011)
by: Falasca, Marco, et al.
Published: (2011)
Key role of phosphoinositide 3-kinase class IB in pancreatic cancer
by: Edling, C., et al.
Published: (2010)
by: Edling, C., et al.
Published: (2010)
Phosphoinositide 3-kinase pathway inhibitors: pharmacology, metabolism & drug development
by: Falasca, Marco
Published: (2011)
by: Falasca, Marco
Published: (2011)
New insight into the intracellular roles of class II phosphoinositide 3-kinases
by: Maffucci, T., et al.
Published: (2014)
by: Maffucci, T., et al.
Published: (2014)
Analysis, regulation, and roles of endosomal phosphoinositides
by: Maffucci, T., et al.
Published: (2014)
by: Maffucci, T., et al.
Published: (2014)
Class II Phosphoinositide 3-Kinases as Novel Drug Targets
by: Falasca, Marco, et al.
Published: (2017)
by: Falasca, Marco, et al.
Published: (2017)
Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic ß cells
by: Dominguez, V., et al.
Published: (2011)
by: Dominguez, V., et al.
Published: (2011)
Investigating the mechanisms of activation and action of phosphoinositide 3-kinase C2 alpha in pancreatic beta cells
by: Mazza, S., et al.
Published: (2013)
by: Mazza, S., et al.
Published: (2013)
Class II phosphoinositide 3-kinase C2ß regulates a novel signaling pathway involved in breast cancer progression.
by: Chikh, A., et al.
Published: (2016)
by: Chikh, A., et al.
Published: (2016)
Class II Phosphoinositide 3-Kinases Contribute to Endothelial Cells Morphogenesis
by: Tibolla, G., et al.
Published: (2013)
by: Tibolla, G., et al.
Published: (2013)
A phosphoinositide 3-kinase/phospholipase cgamma1 pathway regulates fibroblast growth factor-induced capillary tube formation
by: Maffucci, T., et al.
Published: (2009)
by: Maffucci, T., et al.
Published: (2009)
Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway
by: Edling, C., et al.
Published: (2014)
by: Edling, C., et al.
Published: (2014)
Phosphoinositides signalling in cancer: Focus on PI3K and PLC
by: Raimondi, C., et al.
Published: (2012)
by: Raimondi, C., et al.
Published: (2012)
Novel roles for class II Phosphoinositide 3-Kinase C2ß in signalling pathways involved in prostate cancer cell invasion.
by: Mavrommati, I., et al.
Published: (2016)
by: Mavrommati, I., et al.
Published: (2016)
Elucidation of the WNT & AKT/Phosphoinositide-3-Kinase Pathways in Colorectal Carcinoma
by: Khor, Tin Oo
Published: (2004)
by: Khor, Tin Oo
Published: (2004)
Cloning And Promoter Analysis Of Human Choline Kinase Isoforms
by: Yee, Yoke Hiang
Published: (2012)
by: Yee, Yoke Hiang
Published: (2012)
Fine tuning of protein kinase C (PKC) isoforms in cancer: Shortening the distance from the laboratory to the bedside
by: Bosco, R., et al.
Published: (2011)
by: Bosco, R., et al.
Published: (2011)
Functional association of phosphoinositide-3-kinase with platelet glycoprotein Iba, the major ligand-binding subunit of the glycoprotein Ib-IX-V complex
by: Mu, F., et al.
Published: (2010)
by: Mu, F., et al.
Published: (2010)
Construction of baculovirus transfer vectors
for insect cell expression of human choline and
ethanolamine kinase isoforms
by: Chang Chia, Than
Published: (2008)
by: Chang Chia, Than
Published: (2008)
The genetic and epigenetic landscapes of the epithelium in asthma
by: Moheimani, F., et al.
Published: (2016)
by: Moheimani, F., et al.
Published: (2016)
Role and regulation of phosphatidylinositol 3-kinase ß in platelet integrin α2ß1 signaling
by: Consonni, A., et al.
Published: (2012)
by: Consonni, A., et al.
Published: (2012)
Molecular regulation of skeletal muscle myosin heavy chain isoforms
by: Brown, David M.
Published: (2015)
by: Brown, David M.
Published: (2015)
Cudraflavone C induces tumor-specific apoptosis in colorectal cancer cells through inhibition of the phosphoinositide 3-kinase (PI3K)-AKT pathway
by: Castresana, Javier S., et al.
Published: (2017)
by: Castresana, Javier S., et al.
Published: (2017)
Investigation into patterns of epigenetic regulation of Alzheimer’s disease
by: Boden, Kirsty
Published: (2019)
by: Boden, Kirsty
Published: (2019)
The proline-rich tyrosine kinase Pyk2 regulates platelet integrin aIIbß3 outside-in signaling
by: Cipolla, L., et al.
Published: (2013)
by: Cipolla, L., et al.
Published: (2013)
Functional Anatomy of Phospholipid Binding and Regulation of Phosphoinositide Homeostasis by Proteins of the Sec14 Superfamily
by: Schaaf, G., et al.
Published: (2008)
by: Schaaf, G., et al.
Published: (2008)
Esophageal stem cells and genetics/epigenetics in esophageal cancer
by: Croagh, D., et al.
Published: (2014)
by: Croagh, D., et al.
Published: (2014)
Akt/protein kinase B in skeletal muscle physiology and pathology
by: Wu, M., et al.
Published: (2011)
by: Wu, M., et al.
Published: (2011)
Role of ROCK isoforms in regulation of stiffness induced myofibroblast differentiation in lung fibrosis
by: Htwe, Su S., et al.
Published: (2017)
by: Htwe, Su S., et al.
Published: (2017)
Phosphorylation And Regulation
Of Human Choline Kinase Beta
By Protein Kinase A
by: Chang , Ching Ching
Published: (2015)
by: Chang , Ching Ching
Published: (2015)
Phosphorylation And Regulation
Of Human Choline Kinase Beta
By Protein Kinase A
by: Chang , Ching Ching
Published: (2015)
by: Chang , Ching Ching
Published: (2015)
Sec14 like PITPs couple lipid metabolism with phosphoinositide synthesis to regulate golgi functionality
by: Mousley, Carl, et al.
Published: (2015)
by: Mousley, Carl, et al.
Published: (2015)
Analysis of molecular links between epigenetic regulations and energy metabolism
by: Miezaniec, Agata
Published: (2020)
by: Miezaniec, Agata
Published: (2020)
Possible epigenetic role of vitexin in regulating neuroinflammation in Alzheimer’s disease
by: Yahaya, Muhamad Afiq Faisal, et al.
Published: (2020)
by: Yahaya, Muhamad Afiq Faisal, et al.
Published: (2020)
PITPs as targets for selectively interfering with phosphoinositide signaling in cells
by: Nile, A., et al.
Published: (2014)
by: Nile, A., et al.
Published: (2014)
Elucidating the epigenetic roles of notch1 in regulating gata3 and C-MYC in peripheral t cell
lymphomas
by: Al-Khreisat, Mutaz Jamal Abed
Published: (2024)
by: Al-Khreisat, Mutaz Jamal Abed
Published: (2024)
Epigenetic regulation of the secreted frizzled-related protein family in human glioblastoma multiforme
by: Schiefer, L., et al.
Published: (2014)
by: Schiefer, L., et al.
Published: (2014)