Identification of Novel Phytase Genes from an Agricultural Soil-Derived Metagenome

Environmental microorganisms are emerging as an important source of new enzymes for wide-scale industrial application. In this study, novel phytase genes were identified from a soil microbial community. For this, a function-based screening approach was utilized for the identification of phytase acti...

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Main Authors: Tan, H., Mooij, M., Barret, M., Hegarty, P., Harrington, C., Dobson, A., O'Gara, Fergal
Format: Journal Article
Published: The Korean Society for Microbiology 2014
Online Access:http://hdl.handle.net/20.500.11937/4398
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author Tan, H.
Mooij, M.
Barret, M.
Hegarty, P.
Harrington, C.
Dobson, A.
O'Gara, Fergal
author_facet Tan, H.
Mooij, M.
Barret, M.
Hegarty, P.
Harrington, C.
Dobson, A.
O'Gara, Fergal
author_sort Tan, H.
building Curtin Institutional Repository
collection Online Access
description Environmental microorganisms are emerging as an important source of new enzymes for wide-scale industrial application. In this study, novel phytase genes were identified from a soil microbial community. For this, a function-based screening approach was utilized for the identification of phytase activity in a metagenomic library derived from an agricultural soil. Two novel phytases were identified. Interestingly, one of these phytases is an unusual histidine acid phosphatase family phytase, as the conserved motif of the active site of PhyX possesses an additional amino acid residue. The second phytase belongs to a new type, which is encoded by multiple open reading frames (ORFs) and is different to all phytases known to date, which are encoded by a single ORF.
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format Journal Article
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institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T06:02:32Z
publishDate 2014
publisher The Korean Society for Microbiology
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spelling curtin-20.500.11937-43982017-09-13T14:43:27Z Identification of Novel Phytase Genes from an Agricultural Soil-Derived Metagenome Tan, H. Mooij, M. Barret, M. Hegarty, P. Harrington, C. Dobson, A. O'Gara, Fergal Environmental microorganisms are emerging as an important source of new enzymes for wide-scale industrial application. In this study, novel phytase genes were identified from a soil microbial community. For this, a function-based screening approach was utilized for the identification of phytase activity in a metagenomic library derived from an agricultural soil. Two novel phytases were identified. Interestingly, one of these phytases is an unusual histidine acid phosphatase family phytase, as the conserved motif of the active site of PhyX possesses an additional amino acid residue. The second phytase belongs to a new type, which is encoded by multiple open reading frames (ORFs) and is different to all phytases known to date, which are encoded by a single ORF. 2014 Journal Article http://hdl.handle.net/20.500.11937/4398 10.4014/jmb.1307.07007 The Korean Society for Microbiology restricted
spellingShingle Tan, H.
Mooij, M.
Barret, M.
Hegarty, P.
Harrington, C.
Dobson, A.
O'Gara, Fergal
Identification of Novel Phytase Genes from an Agricultural Soil-Derived Metagenome
title Identification of Novel Phytase Genes from an Agricultural Soil-Derived Metagenome
title_full Identification of Novel Phytase Genes from an Agricultural Soil-Derived Metagenome
title_fullStr Identification of Novel Phytase Genes from an Agricultural Soil-Derived Metagenome
title_full_unstemmed Identification of Novel Phytase Genes from an Agricultural Soil-Derived Metagenome
title_short Identification of Novel Phytase Genes from an Agricultural Soil-Derived Metagenome
title_sort identification of novel phytase genes from an agricultural soil-derived metagenome
url http://hdl.handle.net/20.500.11937/4398