Genetic Algorithm based Fuzzy Multiple Regression for the Nocturnal Hypoglycaemia Detection

Low blood glucose (Hypoglycaemia) is dangerous and can result in unconsciousness, seizures and even death. It has a common and serious side effect of insulin therapy in patients with diabetes. We measure physiological parameters (heart rate, corrected QT interval of the electrocardiogram (ECG) signa...

Full description

Bibliographic Details
Main Authors: Ling, S., Nguyen, H., Chan, Kit Yan
Other Authors: Gary Fogel
Format: Conference Paper
Published: IEEE 2010
Online Access:http://hdl.handle.net/20.500.11937/43787
_version_ 1848756808998453248
author Ling, S.
Nguyen, H.
Chan, Kit Yan
author2 Gary Fogel
author_facet Gary Fogel
Ling, S.
Nguyen, H.
Chan, Kit Yan
author_sort Ling, S.
building Curtin Institutional Repository
collection Online Access
description Low blood glucose (Hypoglycaemia) is dangerous and can result in unconsciousness, seizures and even death. It has a common and serious side effect of insulin therapy in patients with diabetes. We measure physiological parameters (heart rate, corrected QT interval of the electrocardiogram (ECG) signal, change of heart rate, and the change of corrected QT interval) continuously to provide detection of hypoglycaemic. Based on these physiological parameters, we have developed a genetic algorithm based multiple regression model to determine the presence of hypoglycaemic episodes. Genetic algorithm is used to determine the optimal parameters of the multiple regression. The overall data were organized into a training set (8 patients) and a testing set (another 8 patient) which are randomly selected. The clinical results show that the proposed algorithm can achieve predictions with good sensitivities and acceptable specificities.
first_indexed 2025-11-14T09:18:05Z
format Conference Paper
id curtin-20.500.11937-43787
institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T09:18:05Z
publishDate 2010
publisher IEEE
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-437872017-09-13T16:00:10Z Genetic Algorithm based Fuzzy Multiple Regression for the Nocturnal Hypoglycaemia Detection Ling, S. Nguyen, H. Chan, Kit Yan Gary Fogel Low blood glucose (Hypoglycaemia) is dangerous and can result in unconsciousness, seizures and even death. It has a common and serious side effect of insulin therapy in patients with diabetes. We measure physiological parameters (heart rate, corrected QT interval of the electrocardiogram (ECG) signal, change of heart rate, and the change of corrected QT interval) continuously to provide detection of hypoglycaemic. Based on these physiological parameters, we have developed a genetic algorithm based multiple regression model to determine the presence of hypoglycaemic episodes. Genetic algorithm is used to determine the optimal parameters of the multiple regression. The overall data were organized into a training set (8 patients) and a testing set (another 8 patient) which are randomly selected. The clinical results show that the proposed algorithm can achieve predictions with good sensitivities and acceptable specificities. 2010 Conference Paper http://hdl.handle.net/20.500.11937/43787 10.1109/CEC.2010.5586315 IEEE fulltext
spellingShingle Ling, S.
Nguyen, H.
Chan, Kit Yan
Genetic Algorithm based Fuzzy Multiple Regression for the Nocturnal Hypoglycaemia Detection
title Genetic Algorithm based Fuzzy Multiple Regression for the Nocturnal Hypoglycaemia Detection
title_full Genetic Algorithm based Fuzzy Multiple Regression for the Nocturnal Hypoglycaemia Detection
title_fullStr Genetic Algorithm based Fuzzy Multiple Regression for the Nocturnal Hypoglycaemia Detection
title_full_unstemmed Genetic Algorithm based Fuzzy Multiple Regression for the Nocturnal Hypoglycaemia Detection
title_short Genetic Algorithm based Fuzzy Multiple Regression for the Nocturnal Hypoglycaemia Detection
title_sort genetic algorithm based fuzzy multiple regression for the nocturnal hypoglycaemia detection
url http://hdl.handle.net/20.500.11937/43787