Genetic Polymorphism of KIR2DL4 (CD158d), a Putative NK Cell Receptor for HLA-G, Does Not Influence Susceptibility to Asthma

Genetic Polymorphism of KIR2DL4 (CD158d), a Putative NK Cell Receptor for HLA-G, Does Not Influence Susceptibility to Asthma

Human leukocyte antigen (HLA)-G is upregulated on the bronchial epithelium of asthma patients and genetic polymorphism affecting expression of HLA-G has been reported to influence susceptibility to asthma. As the NK cell receptor KIR2DL4 has been reported to induce interferon gamma (IFNy) secretion...

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Bibliographic Details
Main Authors: Le Page, M., Goodridge, J., Zhang, Guicheng, Holt, P., Sly, P., Witt, C.
Format: Journal Article
Published: Blackwell Munksgaard 2013
Subjects:
atopy
asthma
KIR2DL4
CD158d
Online Access:http://hdl.handle.net/20.500.11937/43670

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