Macrophage-tropic HIV-1 variants from brain demonstrate alterations in the way gp120 engages both CD4 and CCR5

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Macrophage-tropic HIV-1 variants from brain demonstrate alterations in the way gp120 engages both CD4 and CCR5

BR-derived HIV-1 strains have an exceptional ability to enter macrophages via mechanisms involving their gp120 Env that remain incompletely understood. Here, we used cell-based affinity-profiling methods and mathematical modeling to generate quantitative VERSA metrics that simultaneously measure Env...

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Bibliographic Details
Main Authors:	Salimi, H., Roche, M., Webb, N., Gray, L., Chikere, K., Sterjovski, J., Ellett, A., Wesselingh, S., Ramsland, Paul, Lee, B., Churchill, M., Gorry, P.
Format:	Journal Article
Published:	2013
Online Access:	http://hdl.handle.net/20.500.11937/43385

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