The burden and implications of preoperative atrial fibrillation in Australian heart valve surgery patients

Background Atrial fibrillation (AF) is the most common preoperative arrhythmia in heart valve surgery patients and its prevalence is rising. This study aims to investigate the impact of AF on valve surgery early complications and survival and on valve disease of different aetiologies and populations...

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Main Authors: Russell, E., Walsh, W., Tran, L., Tam, R., Reid, Christopher, Brown, A., Bennetts, J., Baker, R., Maguire, G.
Format: Journal Article
Published: Elsevier Ireland Ltd. 2017
Online Access:http://hdl.handle.net/20.500.11937/43207
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author Russell, E.
Walsh, W.
Tran, L.
Tam, R.
Reid, Christopher
Brown, A.
Bennetts, J.
Baker, R.
Maguire, G.
author_facet Russell, E.
Walsh, W.
Tran, L.
Tam, R.
Reid, Christopher
Brown, A.
Bennetts, J.
Baker, R.
Maguire, G.
author_sort Russell, E.
building Curtin Institutional Repository
collection Online Access
description Background Atrial fibrillation (AF) is the most common preoperative arrhythmia in heart valve surgery patients and its prevalence is rising. This study aims to investigate the impact of AF on valve surgery early complications and survival and on valve disease of different aetiologies and populations with particular reference to Indigenous Australians with rheumatic heart disease (RHD). Methods The Australian and New Zealand Society of Cardiac and Thoracic Surgeons Cardiac Surgery Database was analysed to determine the association between preoperative AF and valve surgery outcome. Its association with demographics, co-morbidities, preoperative status and short and long term outcome was assessed. Results Outcome of 1594 RHD and 19,029 non-RHD-related surgical procedures was analysed. Patients with preoperative AF were more likely to be older, female, Indigenous, to have RHD and to bear a greater burden of comorbidities. Patients with RHD and preoperative AF had a longer hospital stay and were more likely to require reoperation. Adjusted short (OR 1.4, 95% CI 1.2–1.7) and long term (HR 1.5, 95% CI 1.3–1.7) survival was inferior for patients with non-RHD preoperative AF but was no different for Indigenous and non-Indigenous Australians with RHD. Conclusions In this prospective Australian study, patients with valve disease and preoperative AF had inferior short and long term survival. This was particularly the case for patients with non-RHD valve disease. Earlier intervention or more aggressive AF management should be investigated as mechanisms for enhancing postoperative outcomes. This may influence treatment choice and the need for ongoing anticoagulation.
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spelling curtin-20.500.11937-432072017-09-13T15:06:35Z The burden and implications of preoperative atrial fibrillation in Australian heart valve surgery patients Russell, E. Walsh, W. Tran, L. Tam, R. Reid, Christopher Brown, A. Bennetts, J. Baker, R. Maguire, G. Background Atrial fibrillation (AF) is the most common preoperative arrhythmia in heart valve surgery patients and its prevalence is rising. This study aims to investigate the impact of AF on valve surgery early complications and survival and on valve disease of different aetiologies and populations with particular reference to Indigenous Australians with rheumatic heart disease (RHD). Methods The Australian and New Zealand Society of Cardiac and Thoracic Surgeons Cardiac Surgery Database was analysed to determine the association between preoperative AF and valve surgery outcome. Its association with demographics, co-morbidities, preoperative status and short and long term outcome was assessed. Results Outcome of 1594 RHD and 19,029 non-RHD-related surgical procedures was analysed. Patients with preoperative AF were more likely to be older, female, Indigenous, to have RHD and to bear a greater burden of comorbidities. Patients with RHD and preoperative AF had a longer hospital stay and were more likely to require reoperation. Adjusted short (OR 1.4, 95% CI 1.2–1.7) and long term (HR 1.5, 95% CI 1.3–1.7) survival was inferior for patients with non-RHD preoperative AF but was no different for Indigenous and non-Indigenous Australians with RHD. Conclusions In this prospective Australian study, patients with valve disease and preoperative AF had inferior short and long term survival. This was particularly the case for patients with non-RHD valve disease. Earlier intervention or more aggressive AF management should be investigated as mechanisms for enhancing postoperative outcomes. This may influence treatment choice and the need for ongoing anticoagulation. 2017 Journal Article http://hdl.handle.net/20.500.11937/43207 10.1016/j.ijcard.2016.11.070 Elsevier Ireland Ltd. restricted
spellingShingle Russell, E.
Walsh, W.
Tran, L.
Tam, R.
Reid, Christopher
Brown, A.
Bennetts, J.
Baker, R.
Maguire, G.
The burden and implications of preoperative atrial fibrillation in Australian heart valve surgery patients
title The burden and implications of preoperative atrial fibrillation in Australian heart valve surgery patients
title_full The burden and implications of preoperative atrial fibrillation in Australian heart valve surgery patients
title_fullStr The burden and implications of preoperative atrial fibrillation in Australian heart valve surgery patients
title_full_unstemmed The burden and implications of preoperative atrial fibrillation in Australian heart valve surgery patients
title_short The burden and implications of preoperative atrial fibrillation in Australian heart valve surgery patients
title_sort burden and implications of preoperative atrial fibrillation in australian heart valve surgery patients
url http://hdl.handle.net/20.500.11937/43207