Statins inhibit in vitro virulence phenotypes of Pseudomonas aeruginosa

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Statins inhibit in vitro virulence phenotypes of Pseudomonas aeruginosa

Statins are a family of drugs that lower cholesterol levels by inhibiting 3-hydroxy-3-methylglutaryl-CoA-reductase, a rate-limiting enzyme in the human mevalonate pathway of which cholesterol is the biosynthetic end product.1 Statins also have a range of cholesterol-independent effects, including an...

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Bibliographic Details
Main Authors:	Hennessey, E., Mooij, M., Legendre, C., Reen, F., O'Callaghan, J., Adams, C., O'Gara, Fergal
Format:	Journal Article
Published:	Nature Publishing Group 2013
Online Access:	http://hdl.handle.net/20.500.11937/42875

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