Statins inhibit in vitro virulence phenotypes of Pseudomonas aeruginosa
Statins are a family of drugs that lower cholesterol levels by inhibiting 3-hydroxy-3-methylglutaryl-CoA-reductase, a rate-limiting enzyme in the human mevalonate pathway of which cholesterol is the biosynthetic end product.1 Statins also have a range of cholesterol-independent effects, including an...
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Bibliographic Details
| Main Authors: |
Hennessey, E.,
Mooij, M.,
Legendre, C.,
Reen, F.,
O'Callaghan, J.,
Adams, C.,
O'Gara, Fergal |
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| Format: | Journal Article
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| Published: |
Nature Publishing Group
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/42875
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