Bioconversion of α-linolenic acid into n-3 long-chain polyunsaturated fatty acid in hepatocytes and ad hoc cell culture optimisation

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Bioconversion of α-linolenic acid into n-3 long-chain polyunsaturated fatty acid in hepatocytes and ad hoc cell culture optimisation

This study aimed to establish optimal conditions for a cell culture system that would allow the measurement of 18:3n-3 (ALA) bioconversion into n-3 long-chain polyunsaturated fatty acid (n-3 LC-PUFA), and to determine the overall pathway kinetics. Using rat hepatocytes (FaO) as model cells, it was e...

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Bibliographic Details
Main Authors:	Alhazzaa, Ramez, Sinclair, A., Turchini, G.
Format:	Journal Article
Published:	Public Library of Science 2013
Online Access:	http://hdl.handle.net/20.500.11937/42857

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