Thymic tissue is not evident on high-resolution computed tomography and [18F]Fluoro-deoxy-glucose positron emission tomography scans of aviraemic HIV patients with poor recovery of CD4 + T cells
Some previously immunodeficient HIV patients responding to antiretroviral therapy display poor recovery of CD4 + T cells. Evaluation of the contribution of thymic function requires sensitive detection and quantitation of metabolically active thymic tissue. We describe patient...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
| Published: |
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/42628 |
| _version_ | 1848756473241272320 |
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| author | Tanaskovic, S. Fernandez, S. French, M. Price, R. Song, S. Robins, P. Price, Patricia |
| author_facet | Tanaskovic, S. Fernandez, S. French, M. Price, R. Song, S. Robins, P. Price, Patricia |
| author_sort | Tanaskovic, S. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Some previously immunodeficient HIV patients responding to antiretroviral therapy display poor recovery of CD4 + T cells. Evaluation of the contribution of thymic function requires sensitive detection and quantitation of metabolically active thymic tissue. We describe patients with low but detectable thymopoiesis assessed as circulating CD4 + naive T cells expressing CD31. High-resolution computed tomography and PET scans found no residual thymic tissue even though metabolic activity was demonstrable by PET in lymph nodes. |
| first_indexed | 2025-11-14T09:12:45Z |
| format | Journal Article |
| id | curtin-20.500.11937-42628 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:12:45Z |
| publishDate | 2011 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-426282018-04-19T07:15:33Z Thymic tissue is not evident on high-resolution computed tomography and [18F]Fluoro-deoxy-glucose positron emission tomography scans of aviraemic HIV patients with poor recovery of CD4 + T cells Tanaskovic, S. Fernandez, S. French, M. Price, R. Song, S. Robins, P. Price, Patricia Some previously immunodeficient HIV patients responding to antiretroviral therapy display poor recovery of CD4 + T cells. Evaluation of the contribution of thymic function requires sensitive detection and quantitation of metabolically active thymic tissue. We describe patients with low but detectable thymopoiesis assessed as circulating CD4 + naive T cells expressing CD31. High-resolution computed tomography and PET scans found no residual thymic tissue even though metabolic activity was demonstrable by PET in lymph nodes. 2011 Journal Article http://hdl.handle.net/20.500.11937/42628 10.1097/QAD.0b013e3283474155 unknown |
| spellingShingle | Tanaskovic, S. Fernandez, S. French, M. Price, R. Song, S. Robins, P. Price, Patricia Thymic tissue is not evident on high-resolution computed tomography and [18F]Fluoro-deoxy-glucose positron emission tomography scans of aviraemic HIV patients with poor recovery of CD4 + T cells |
| title | Thymic tissue is not evident on high-resolution computed tomography and [18F]Fluoro-deoxy-glucose positron emission tomography scans of aviraemic HIV patients with poor recovery of CD4 + T cells |
| title_full | Thymic tissue is not evident on high-resolution computed tomography and [18F]Fluoro-deoxy-glucose positron emission tomography scans of aviraemic HIV patients with poor recovery of CD4 + T cells |
| title_fullStr | Thymic tissue is not evident on high-resolution computed tomography and [18F]Fluoro-deoxy-glucose positron emission tomography scans of aviraemic HIV patients with poor recovery of CD4 + T cells |
| title_full_unstemmed | Thymic tissue is not evident on high-resolution computed tomography and [18F]Fluoro-deoxy-glucose positron emission tomography scans of aviraemic HIV patients with poor recovery of CD4 + T cells |
| title_short | Thymic tissue is not evident on high-resolution computed tomography and [18F]Fluoro-deoxy-glucose positron emission tomography scans of aviraemic HIV patients with poor recovery of CD4 + T cells |
| title_sort | thymic tissue is not evident on high-resolution computed tomography and [18f]fluoro-deoxy-glucose positron emission tomography scans of aviraemic hiv patients with poor recovery of cd4 + t cells |
| url | http://hdl.handle.net/20.500.11937/42628 |