L-Arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge

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L-Arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge

In this work, our aim was to determine whether L-arginine (a known insulinotropic amino acid) can promote a shift of β-cell intermediary metabolism favoring glutathione (GSH) and glutathione disulfide (GSSG) antioxidant responses, stimulus–secretion coupling and functional integrity. Clonal BRIN-BD1...

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Bibliographic Details
Main Authors:	Krause, M., McClenaghan, N., Flatt, P., Hamem de Bittencourt, P., Murphy, C., Newsholme, Philip
Format:	Journal Article
Published:	BioScientifica Ltd. 2011
Online Access:	http://hdl.handle.net/20.500.11937/42587

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