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Stabilization of resveratrol in blood circulation by conjugation to mPEG and mPEG-PLA polymers: Investigation of conjugate linker and polymer composition on stability, metabolism, antioxidant activity and pharmacokinetic profile

Resveratrol is naturally occurring phytochemical with diverse biological activities such as chemoprevention, anti-inflammatory, anti-cancer, anti-oxidant. But undergoes rapid metabolism in the body (half life 0.13h). Hence Polymer conjugation utilizing different chemical linkers and polymer composit...

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Bibliographic Details
Main Authors:	Siddalingappa, B., Benson, Heather, Brown, D., Batty, Kevin, Chen, Y.
Format:	Journal Article
Published:	Public Library of Science 2015
Online Access:	http://hdl.handle.net/20.500.11937/42523

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