Capillary Electrophoresis in Forensic Chemistry

The separation and quantification of chemical substances in a wide variety of complex matrices is a significant analytical challenge to the forensic chemist. Capillary electrophoresis (CE) is attractive to the forensic chemist as it has the potential to provide exceptional separating power in combin...

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Bibliographic Details
Main Authors: Tagliaro, F., Pascali, J., Lewis, Simon
Other Authors: Jay A Siegel
Format: Book Chapter
Published: Academic Press 2013
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/42425
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author Tagliaro, F.
Pascali, J.
Lewis, Simon
author2 Jay A Siegel
author_facet Jay A Siegel
Tagliaro, F.
Pascali, J.
Lewis, Simon
author_sort Tagliaro, F.
building Curtin Institutional Repository
collection Online Access
description The separation and quantification of chemical substances in a wide variety of complex matrices is a significant analytical challenge to the forensic chemist. Capillary electrophoresis (CE) is attractive to the forensic chemist as it has the potential to provide exceptional separating power in combination with rapid analysis times and high mass sensitivities. It is also economical of both reagents and sample. Owing to the variety of separation modes possible (electrophoretic, electrokinetic, chromatography-like, etc.) and the detection systems available (UV–visible absorbance, luminescence, and mass spectrometry are all available commercially), it is applicable to the determination of a wide variety of chemical substances including inorganic ions, small organic molecules, chiral compounds, macromolecules, and intact viruses and cells. This article provides an overview of the application of CE to forensic chemical analysis, illustrated with recent examples.
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spelling curtin-20.500.11937-424252023-02-13T08:01:35Z Capillary Electrophoresis in Forensic Chemistry Tagliaro, F. Pascali, J. Lewis, Simon Jay A Siegel Pekka J Saukko Inks Illicit drugs Capillary electrophoresis Gunshot residue Miniaturization Forensic medicine Explosives Toxicology The separation and quantification of chemical substances in a wide variety of complex matrices is a significant analytical challenge to the forensic chemist. Capillary electrophoresis (CE) is attractive to the forensic chemist as it has the potential to provide exceptional separating power in combination with rapid analysis times and high mass sensitivities. It is also economical of both reagents and sample. Owing to the variety of separation modes possible (electrophoretic, electrokinetic, chromatography-like, etc.) and the detection systems available (UV–visible absorbance, luminescence, and mass spectrometry are all available commercially), it is applicable to the determination of a wide variety of chemical substances including inorganic ions, small organic molecules, chiral compounds, macromolecules, and intact viruses and cells. This article provides an overview of the application of CE to forensic chemical analysis, illustrated with recent examples. 2013 Book Chapter http://hdl.handle.net/20.500.11937/42425 10.1016/B978-0-12-382165-2.00243-9 Academic Press restricted
spellingShingle Inks
Illicit drugs
Capillary electrophoresis
Gunshot residue
Miniaturization
Forensic medicine
Explosives
Toxicology
Tagliaro, F.
Pascali, J.
Lewis, Simon
Capillary Electrophoresis in Forensic Chemistry
title Capillary Electrophoresis in Forensic Chemistry
title_full Capillary Electrophoresis in Forensic Chemistry
title_fullStr Capillary Electrophoresis in Forensic Chemistry
title_full_unstemmed Capillary Electrophoresis in Forensic Chemistry
title_short Capillary Electrophoresis in Forensic Chemistry
title_sort capillary electrophoresis in forensic chemistry
topic Inks
Illicit drugs
Capillary electrophoresis
Gunshot residue
Miniaturization
Forensic medicine
Explosives
Toxicology
url http://hdl.handle.net/20.500.11937/42425