Clinical and molecular epidemiology of community-onset invasive Staphylococcus aureus infection in New Zealand children
Our aim was to describe the epidemiology and incidence of community-onset invasive S. aureus disease in children presenting to our hospital, and to compare the clonal complexes and virulence genes of S. aureus strains causing invasive and non-invasive disease. The virulence gene repertoire of invasi...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
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Cambridge University Press
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/42385 |
| _version_ | 1848756405297741824 |
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| author | Williamson, D. Ritchie, S. Roberts, S. Coombs, Geoffrey Thomas, M. Hannaford, O. Baker, M. Lennon, D. Fraser, J. |
| author_facet | Williamson, D. Ritchie, S. Roberts, S. Coombs, Geoffrey Thomas, M. Hannaford, O. Baker, M. Lennon, D. Fraser, J. |
| author_sort | Williamson, D. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Our aim was to describe the epidemiology and incidence of community-onset invasive S. aureus disease in children presenting to our hospital, and to compare the clonal complexes and virulence genes of S. aureus strains causing invasive and non-invasive disease. The virulence gene repertoire of invasive disease isolates was characterized using DNA microarray and compared with the virulence gene repertoire of non-invasive S. aureus isolates. Over the study period, 163 children had an invasive S. aureus infection. There was no difference in the distribution of clonal complexes or in the prevalence of genes encoding virulence factors between invasive and non-invasive isolates. Future research should include a strong focus on identifying the host and environmental factors that, along with organism virulence factors, are contributing to the patterns of invasive S. aureus disease observed in New Zealand. |
| first_indexed | 2025-11-14T09:11:40Z |
| format | Journal Article |
| id | curtin-20.500.11937-42385 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:11:40Z |
| publishDate | 2014 |
| publisher | Cambridge University Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-423852017-09-13T14:26:48Z Clinical and molecular epidemiology of community-onset invasive Staphylococcus aureus infection in New Zealand children Williamson, D. Ritchie, S. Roberts, S. Coombs, Geoffrey Thomas, M. Hannaford, O. Baker, M. Lennon, D. Fraser, J. Paediatrics Staphylococcus aureus statistics Our aim was to describe the epidemiology and incidence of community-onset invasive S. aureus disease in children presenting to our hospital, and to compare the clonal complexes and virulence genes of S. aureus strains causing invasive and non-invasive disease. The virulence gene repertoire of invasive disease isolates was characterized using DNA microarray and compared with the virulence gene repertoire of non-invasive S. aureus isolates. Over the study period, 163 children had an invasive S. aureus infection. There was no difference in the distribution of clonal complexes or in the prevalence of genes encoding virulence factors between invasive and non-invasive isolates. Future research should include a strong focus on identifying the host and environmental factors that, along with organism virulence factors, are contributing to the patterns of invasive S. aureus disease observed in New Zealand. 2014 Journal Article http://hdl.handle.net/20.500.11937/42385 10.1017/S0950268814000053 Cambridge University Press restricted |
| spellingShingle | Paediatrics Staphylococcus aureus statistics Williamson, D. Ritchie, S. Roberts, S. Coombs, Geoffrey Thomas, M. Hannaford, O. Baker, M. Lennon, D. Fraser, J. Clinical and molecular epidemiology of community-onset invasive Staphylococcus aureus infection in New Zealand children |
| title | Clinical and molecular epidemiology of community-onset invasive Staphylococcus aureus infection in New Zealand children |
| title_full | Clinical and molecular epidemiology of community-onset invasive Staphylococcus aureus infection in New Zealand children |
| title_fullStr | Clinical and molecular epidemiology of community-onset invasive Staphylococcus aureus infection in New Zealand children |
| title_full_unstemmed | Clinical and molecular epidemiology of community-onset invasive Staphylococcus aureus infection in New Zealand children |
| title_short | Clinical and molecular epidemiology of community-onset invasive Staphylococcus aureus infection in New Zealand children |
| title_sort | clinical and molecular epidemiology of community-onset invasive staphylococcus aureus infection in new zealand children |
| topic | Paediatrics Staphylococcus aureus statistics |
| url | http://hdl.handle.net/20.500.11937/42385 |