A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

The embryonic programme 'epithelial-mesenchymal transition' (EMT) is thought to promote malignant tumour progression. The transcriptional repressor zinc-finger E-box binding homeobox 1 (ZEB1) is a crucial inducer of EMT in various human tumours, and was recently shown to promote invasion a...

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Bibliographic Details
Main Authors: Burk, U., Schubert, J., Wellner, U., Schmalhofer, O., Vincan, Elizabeth, Spaderna, S., Brabletz, T.
Format: Journal Article
Published: 2008
Online Access:http://hdl.handle.net/20.500.11937/42318

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