Selective functionalization of hollow nanospheres with acid and base groups for cascade reactions

The inner-surface functionalization of hollow silica spheres has rarely been reported and is still a challenging topic. Herein, we report a deacetalization–Henry cascade reaction catalyzed by dual-functionalized mesoporous silica hollow nanospheres with basic amine groups ([BOND]NH2) on the internal...

Full description

Bibliographic Details
Main Authors: Gao, J., Zhang, X., Lu, Y., Liu, Shaomin, Liu, Jian
Format: Journal Article
Published: Wiley-VCH Verlag 2015
Online Access:http://hdl.handle.net/20.500.11937/42298
_version_ 1848756381681713152
author Gao, J.
Zhang, X.
Lu, Y.
Liu, Shaomin
Liu, Jian
author_facet Gao, J.
Zhang, X.
Lu, Y.
Liu, Shaomin
Liu, Jian
author_sort Gao, J.
building Curtin Institutional Repository
collection Online Access
description The inner-surface functionalization of hollow silica spheres has rarely been reported and is still a challenging topic. Herein, we report a deacetalization–Henry cascade reaction catalyzed by dual-functionalized mesoporous silica hollow nanospheres with basic amine groups ([BOND]NH2) on the internal shell and carboxylic acid groups ([BOND]COOH) on the external shell. The selective functionalization has been realized by a combination of “step-by-step post-grafting” and “cationic surfactant-assisted selective etching” strategy. Compared to unisolated catalyst, the selectively isolated acidic and basic dual catalyst provides excellent catalytic performance for the deacetalization–Henry cascade reaction in terms of both activity (>99 %) and selectivity (95 %).
first_indexed 2025-11-14T09:11:18Z
format Journal Article
id curtin-20.500.11937-42298
institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T09:11:18Z
publishDate 2015
publisher Wiley-VCH Verlag
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-422982017-09-13T14:23:34Z Selective functionalization of hollow nanospheres with acid and base groups for cascade reactions Gao, J. Zhang, X. Lu, Y. Liu, Shaomin Liu, Jian The inner-surface functionalization of hollow silica spheres has rarely been reported and is still a challenging topic. Herein, we report a deacetalization–Henry cascade reaction catalyzed by dual-functionalized mesoporous silica hollow nanospheres with basic amine groups ([BOND]NH2) on the internal shell and carboxylic acid groups ([BOND]COOH) on the external shell. The selective functionalization has been realized by a combination of “step-by-step post-grafting” and “cationic surfactant-assisted selective etching” strategy. Compared to unisolated catalyst, the selectively isolated acidic and basic dual catalyst provides excellent catalytic performance for the deacetalization–Henry cascade reaction in terms of both activity (>99 %) and selectivity (95 %). 2015 Journal Article http://hdl.handle.net/20.500.11937/42298 10.1002/chem.201500532 Wiley-VCH Verlag restricted
spellingShingle Gao, J.
Zhang, X.
Lu, Y.
Liu, Shaomin
Liu, Jian
Selective functionalization of hollow nanospheres with acid and base groups for cascade reactions
title Selective functionalization of hollow nanospheres with acid and base groups for cascade reactions
title_full Selective functionalization of hollow nanospheres with acid and base groups for cascade reactions
title_fullStr Selective functionalization of hollow nanospheres with acid and base groups for cascade reactions
title_full_unstemmed Selective functionalization of hollow nanospheres with acid and base groups for cascade reactions
title_short Selective functionalization of hollow nanospheres with acid and base groups for cascade reactions
title_sort selective functionalization of hollow nanospheres with acid and base groups for cascade reactions
url http://hdl.handle.net/20.500.11937/42298