Selective functionalization of hollow nanospheres with acid and base groups for cascade reactions
The inner-surface functionalization of hollow silica spheres has rarely been reported and is still a challenging topic. Herein, we report a deacetalization–Henry cascade reaction catalyzed by dual-functionalized mesoporous silica hollow nanospheres with basic amine groups ([BOND]NH2) on the internal...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Published: |
Wiley-VCH Verlag
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/42298 |
| Summary: | The inner-surface functionalization of hollow silica spheres has rarely been reported and is still a challenging topic. Herein, we report a deacetalization–Henry cascade reaction catalyzed by dual-functionalized mesoporous silica hollow nanospheres with basic amine groups ([BOND]NH2) on the internal shell and carboxylic acid groups ([BOND]COOH) on the external shell. The selective functionalization has been realized by a combination of “step-by-step post-grafting” and “cationic surfactant-assisted selective etching” strategy. Compared to unisolated catalyst, the selectively isolated acidic and basic dual catalyst provides excellent catalytic performance for the deacetalization–Henry cascade reaction in terms of both activity (>99 %) and selectivity (95 %). |
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