An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation

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An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation

Therapy resistance is one of the major impediments to successful cancer treatment. In breast cancer, a small subpopulation of cells with stem cell features, named breast cancer stem cells (BCSC), is responsible for metastasis and recurrence of the tumor. BCSC have the unique ability to grow under no...

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Bibliographic Details
Main Authors:	Smit, L., Berns, K., Spence, K., Ryder, W., Zeps, Nikolajs, Madiredjo, M., Beijersbergen, R., Bernards, R., Clarke, R.
Format:	Journal Article
Published:	2015
Online Access:	http://hdl.handle.net/20.500.11937/4190

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