Saturated and unsaturated (including arachidonic acid) non-esterified fatty acid modulation of insulin secretion from pancreatic ß-cells

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Saturated and unsaturated (including arachidonic acid) non-esterified fatty acid modulation of insulin secretion from pancreatic ß-cells

Both stimulatory and detrimental effects of NEFAS (non-esterified fatty acids) on pancreatic ß-cells have been recognized. Acute exposure of the pancreatic ß-cell to high glucose concentrations and/or saturated NEFAs results in a substantial increase in insulin release, whereas chronic exposure resu...

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Bibliographic Details
Main Authors:	Keane, D., Newsholme, Philip
Format:	Journal Article
Published:	Portland Press Ltd. 2008
Online Access:	http://hdl.handle.net/20.500.11937/41620

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