Is aversive learning a marker of risk for anxiety disorders in children?

Aversive conditioning and extinction were evaluated in children with anxiety disorders (n=23), at-risk for anxiety disorders (n=15), and controls (n=11). Participants underwent 16 trials of discriminative conditioning of two geometric figures, with (CS+) or without (CS-) an aversive tone (US), follo...

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Main Authors: Craske, M., Waters, A., Lindsey Bergman, R., Naliboff, B., Lipp, Ottmar, Negoro, H., Ornitz, E.
Format: Journal Article
Published: Elsevier 2008
Online Access:http://hdl.handle.net/20.500.11937/41479
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author Craske, M.
Waters, A.
Lindsey Bergman, R.
Naliboff, B.
Lipp, Ottmar
Negoro, H.
Ornitz, E.
author_facet Craske, M.
Waters, A.
Lindsey Bergman, R.
Naliboff, B.
Lipp, Ottmar
Negoro, H.
Ornitz, E.
author_sort Craske, M.
building Curtin Institutional Repository
collection Online Access
description Aversive conditioning and extinction were evaluated in children with anxiety disorders (n=23), at-risk for anxiety disorders (n=15), and controls (n=11). Participants underwent 16 trials of discriminative conditioning of two geometric figures, with (CS+) or without (CS-) an aversive tone (US), followed by 8 extinction trials (4 CS+, 4 CS-), and 8 extinction re-test trials averaging 2 weeks later. Skin conductance responses and verbal ratings of valence and arousal to the CS+/CS- stimuli were measured. Anxiety disordered children showed larger anticipatory and unconditional skin conductance responses across conditioning, and larger orienting and anticipatory skin conductance responses across extinction and extinction re-test, all to the CS+ and CS-, relative to controls. At-risk children showed larger unconditional responses during conditioning, larger orienting responses during the first block of extinction, and larger anticipatory responses during extinction re-test, all to the CS+ and CS-, relative to controls. Also, anxiety disordered children rated the CS+ as more unpleasant than the other groups. Elevated skin conductance responses to signals of threat (CS+) and signals of safety (CS-; CS+ during extinction) are discussed as features of manifestation of and risk for anxiety in children, compared to the specificity of valence judgments to the manifestation of anxiety.
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spelling curtin-20.500.11937-414792018-03-29T09:07:10Z Is aversive learning a marker of risk for anxiety disorders in children? Craske, M. Waters, A. Lindsey Bergman, R. Naliboff, B. Lipp, Ottmar Negoro, H. Ornitz, E. Aversive conditioning and extinction were evaluated in children with anxiety disorders (n=23), at-risk for anxiety disorders (n=15), and controls (n=11). Participants underwent 16 trials of discriminative conditioning of two geometric figures, with (CS+) or without (CS-) an aversive tone (US), followed by 8 extinction trials (4 CS+, 4 CS-), and 8 extinction re-test trials averaging 2 weeks later. Skin conductance responses and verbal ratings of valence and arousal to the CS+/CS- stimuli were measured. Anxiety disordered children showed larger anticipatory and unconditional skin conductance responses across conditioning, and larger orienting and anticipatory skin conductance responses across extinction and extinction re-test, all to the CS+ and CS-, relative to controls. At-risk children showed larger unconditional responses during conditioning, larger orienting responses during the first block of extinction, and larger anticipatory responses during extinction re-test, all to the CS+ and CS-, relative to controls. Also, anxiety disordered children rated the CS+ as more unpleasant than the other groups. Elevated skin conductance responses to signals of threat (CS+) and signals of safety (CS-; CS+ during extinction) are discussed as features of manifestation of and risk for anxiety in children, compared to the specificity of valence judgments to the manifestation of anxiety. 2008 Journal Article http://hdl.handle.net/20.500.11937/41479 10.1016/j.brat.2008.04.011 Elsevier restricted
spellingShingle Craske, M.
Waters, A.
Lindsey Bergman, R.
Naliboff, B.
Lipp, Ottmar
Negoro, H.
Ornitz, E.
Is aversive learning a marker of risk for anxiety disorders in children?
title Is aversive learning a marker of risk for anxiety disorders in children?
title_full Is aversive learning a marker of risk for anxiety disorders in children?
title_fullStr Is aversive learning a marker of risk for anxiety disorders in children?
title_full_unstemmed Is aversive learning a marker of risk for anxiety disorders in children?
title_short Is aversive learning a marker of risk for anxiety disorders in children?
title_sort is aversive learning a marker of risk for anxiety disorders in children?
url http://hdl.handle.net/20.500.11937/41479