Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls

Evidence that fructose intake may modify blood pressure is generally limited to adult populations. This study examined cross-sectional associations between dietary intake of fructose, serum uric acid and blood pressure in 814 adolescents aged 13–15 years participating in the Western Australian Pregn...

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Main Authors: Bobridge, K., Haines, G., Mori, T., Beilin, L., Oddy, W., Sherriff, Jillian, O'Sullivan, T.
Format: Journal Article
Published: Nature Publishing Group 2013
Online Access:http://hdl.handle.net/20.500.11937/41462
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author Bobridge, K.
Haines, G.
Mori, T.
Beilin, L.
Oddy, W.
Sherriff, Jillian
O'Sullivan, T.
author_facet Bobridge, K.
Haines, G.
Mori, T.
Beilin, L.
Oddy, W.
Sherriff, Jillian
O'Sullivan, T.
author_sort Bobridge, K.
building Curtin Institutional Repository
collection Online Access
description Evidence that fructose intake may modify blood pressure is generally limited to adult populations. This study examined cross-sectional associations between dietary intake of fructose, serum uric acid and blood pressure in 814 adolescents aged 13–15 years participating in the Western Australian Pregnancy Cohort (Raine) Study. Energy-adjusted fructose intake was derived from 3-day food records, serum uric acid concentration was assessed using fasting blood and resting blood pressure was determined using repeated oscillometric readings. In multivariate linear regression models, we did not see a significant association between fructose and blood pressure in boys or girls. In boys, fructose intake was independently associated with serum uric acid (P<0.01), and serum uric acid was independently associated with systolic blood pressure (P<0.01) and mean arterial pressure (P<0.001). Although there are independent associations, there is no direct relationship between fructose intake and blood pressure. Our data suggest that gender may influence these relationships in adolescence, with significant associations observed more frequently in boys than girls.
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spelling curtin-20.500.11937-414622017-09-13T16:01:26Z Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls Bobridge, K. Haines, G. Mori, T. Beilin, L. Oddy, W. Sherriff, Jillian O'Sullivan, T. Evidence that fructose intake may modify blood pressure is generally limited to adult populations. This study examined cross-sectional associations between dietary intake of fructose, serum uric acid and blood pressure in 814 adolescents aged 13–15 years participating in the Western Australian Pregnancy Cohort (Raine) Study. Energy-adjusted fructose intake was derived from 3-day food records, serum uric acid concentration was assessed using fasting blood and resting blood pressure was determined using repeated oscillometric readings. In multivariate linear regression models, we did not see a significant association between fructose and blood pressure in boys or girls. In boys, fructose intake was independently associated with serum uric acid (P<0.01), and serum uric acid was independently associated with systolic blood pressure (P<0.01) and mean arterial pressure (P<0.001). Although there are independent associations, there is no direct relationship between fructose intake and blood pressure. Our data suggest that gender may influence these relationships in adolescence, with significant associations observed more frequently in boys than girls. 2013 Journal Article http://hdl.handle.net/20.500.11937/41462 10.1038/jhh.2012.36 Nature Publishing Group fulltext
spellingShingle Bobridge, K.
Haines, G.
Mori, T.
Beilin, L.
Oddy, W.
Sherriff, Jillian
O'Sullivan, T.
Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls
title Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls
title_full Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls
title_fullStr Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls
title_full_unstemmed Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls
title_short Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls
title_sort dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls
url http://hdl.handle.net/20.500.11937/41462