Enterobacteriaceae Sepsis Outcome Programme annual report, 2013

The Australian Group on Antimicrobial Resistance performs regular period-prevalence studies to monitor changes in antimicrobial resistance in selected enteric Gram-negative pathogens. The 2013 survey focussed for the first time on blood stream infections. Four thousand nine hundred and fifty-eight E...

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Main Authors: Turnidge, J., Gottlieb, T., Mitchell, D., Coombs, Geoffrey, Daley, D., Bell, J.
Format: Journal Article
Published: 2014
Online Access:http://hdl.handle.net/20.500.11937/41357
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author Turnidge, J.
Gottlieb, T.
Mitchell, D.
Coombs, Geoffrey
Daley, D.
Bell, J.
author_facet Turnidge, J.
Gottlieb, T.
Mitchell, D.
Coombs, Geoffrey
Daley, D.
Bell, J.
author_sort Turnidge, J.
building Curtin Institutional Repository
collection Online Access
description The Australian Group on Antimicrobial Resistance performs regular period-prevalence studies to monitor changes in antimicrobial resistance in selected enteric Gram-negative pathogens. The 2013 survey focussed for the first time on blood stream infections. Four thousand nine hundred and fifty-eight Enterobacteriaceae species were tested using commercial automated methods (Vitek® 2, BioMérieux; Phoenix™, BD). The results were analysed using Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) breakpoints (January 2014). Of the key resistances, non-susceptibility to the third-generation cephalosporin, ceftriaxone, was found in 7.5%/7.5% (CLSI/EUCAST criteria respectively) of Escherichia coli; 6.3%/6.3% of Klebsiella pneumoniae, and 7.4%/7.4% of K. oxytoca. Non-susceptibility rates to ciprofloxacin were 10.3%/11.3% for E. coli, 4.6%/7.5% for K. pneumoniae, 0.6%/0.6% for K. oxytoca, and 3.6%/6.1% in Enterobacter cloacae. Resistance rates to piperacillin-tazobactam were 3.1%/6.2%, 4.2%/7.0%, 11.9% /12.6%, and 17.3% /22.2% for the same 4 species respectively. Fourteen isolates were shown to harbour a carbapenemase gene, 9 blaIMP, 3 blaKPC, and 2 blaNDM.
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spelling curtin-20.500.11937-413572017-01-30T14:50:56Z Enterobacteriaceae Sepsis Outcome Programme annual report, 2013 Turnidge, J. Gottlieb, T. Mitchell, D. Coombs, Geoffrey Daley, D. Bell, J. The Australian Group on Antimicrobial Resistance performs regular period-prevalence studies to monitor changes in antimicrobial resistance in selected enteric Gram-negative pathogens. The 2013 survey focussed for the first time on blood stream infections. Four thousand nine hundred and fifty-eight Enterobacteriaceae species were tested using commercial automated methods (Vitek® 2, BioMérieux; Phoenix™, BD). The results were analysed using Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) breakpoints (January 2014). Of the key resistances, non-susceptibility to the third-generation cephalosporin, ceftriaxone, was found in 7.5%/7.5% (CLSI/EUCAST criteria respectively) of Escherichia coli; 6.3%/6.3% of Klebsiella pneumoniae, and 7.4%/7.4% of K. oxytoca. Non-susceptibility rates to ciprofloxacin were 10.3%/11.3% for E. coli, 4.6%/7.5% for K. pneumoniae, 0.6%/0.6% for K. oxytoca, and 3.6%/6.1% in Enterobacter cloacae. Resistance rates to piperacillin-tazobactam were 3.1%/6.2%, 4.2%/7.0%, 11.9% /12.6%, and 17.3% /22.2% for the same 4 species respectively. Fourteen isolates were shown to harbour a carbapenemase gene, 9 blaIMP, 3 blaKPC, and 2 blaNDM. 2014 Journal Article http://hdl.handle.net/20.500.11937/41357 restricted
spellingShingle Turnidge, J.
Gottlieb, T.
Mitchell, D.
Coombs, Geoffrey
Daley, D.
Bell, J.
Enterobacteriaceae Sepsis Outcome Programme annual report, 2013
title Enterobacteriaceae Sepsis Outcome Programme annual report, 2013
title_full Enterobacteriaceae Sepsis Outcome Programme annual report, 2013
title_fullStr Enterobacteriaceae Sepsis Outcome Programme annual report, 2013
title_full_unstemmed Enterobacteriaceae Sepsis Outcome Programme annual report, 2013
title_short Enterobacteriaceae Sepsis Outcome Programme annual report, 2013
title_sort enterobacteriaceae sepsis outcome programme annual report, 2013
url http://hdl.handle.net/20.500.11937/41357