Ontology-based support for human disease study
In this paper, we discuss an ontology-based system and approach that provides interoperability support for research in, and diagnosis of, human disease. The proposed solution incorporates a prototype for a GENERIC HUMAN DISEASE ONTOLOGY that contains common general information regarding human diseas...
| Main Authors: | , |
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| Format: | Conference Paper |
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IEEE
2005
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| Online Access: | http://hdl.handle.net/20.500.11937/41098 |
| _version_ | 1848756050186993664 |
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| author | Hadzic, Maja Chang, Elizabeth |
| author_facet | Hadzic, Maja Chang, Elizabeth |
| author_sort | Hadzic, Maja |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | In this paper, we discuss an ontology-based system and approach that provides interoperability support for research in, and diagnosis of, human disease. The proposed solution incorporates a prototype for a GENERIC HUMAN DISEASE ONTOLOGY that contains common general information regarding human diseases. This proposed Generic Human Disease Ontology represents the information in 4 ?dimensions?: (1) disease types, (2) phenotype (observable characteristics of an organism) or symptoms (3) causes related to the disease, namely genetic causes (genes, gene complexes and DNA regions of interest) and environmental causes (such as stress, family condition, drugs, climate etc.), and (4) treatments available for the disease such as drug therapy, chemotherapy, physiotherapy, psychotherapy, surgery etc. The Generic Human Disease Ontology aims to support also the study of complex disorders caused by many different factors simultaneously e.g. the case of manic depressive disorders. We illustrate how this Generic Human Disease Ontology helps to produce Generic Human Disease Ontology on request, as support tool for physicians and medical researchers. |
| first_indexed | 2025-11-14T09:06:02Z |
| format | Conference Paper |
| id | curtin-20.500.11937-41098 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:06:02Z |
| publishDate | 2005 |
| publisher | IEEE |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-410982017-01-30T14:48:09Z Ontology-based support for human disease study Hadzic, Maja Chang, Elizabeth human disease Unified Medical Language System human disease study ontology generic human disease bi-polar disorder DNA information systems manic depression UMLS In this paper, we discuss an ontology-based system and approach that provides interoperability support for research in, and diagnosis of, human disease. The proposed solution incorporates a prototype for a GENERIC HUMAN DISEASE ONTOLOGY that contains common general information regarding human diseases. This proposed Generic Human Disease Ontology represents the information in 4 ?dimensions?: (1) disease types, (2) phenotype (observable characteristics of an organism) or symptoms (3) causes related to the disease, namely genetic causes (genes, gene complexes and DNA regions of interest) and environmental causes (such as stress, family condition, drugs, climate etc.), and (4) treatments available for the disease such as drug therapy, chemotherapy, physiotherapy, psychotherapy, surgery etc. The Generic Human Disease Ontology aims to support also the study of complex disorders caused by many different factors simultaneously e.g. the case of manic depressive disorders. We illustrate how this Generic Human Disease Ontology helps to produce Generic Human Disease Ontology on request, as support tool for physicians and medical researchers. 2005 Conference Paper http://hdl.handle.net/20.500.11937/41098 IEEE fulltext |
| spellingShingle | human disease Unified Medical Language System human disease study ontology generic human disease bi-polar disorder DNA information systems manic depression UMLS Hadzic, Maja Chang, Elizabeth Ontology-based support for human disease study |
| title | Ontology-based support for human disease study |
| title_full | Ontology-based support for human disease study |
| title_fullStr | Ontology-based support for human disease study |
| title_full_unstemmed | Ontology-based support for human disease study |
| title_short | Ontology-based support for human disease study |
| title_sort | ontology-based support for human disease study |
| topic | human disease Unified Medical Language System human disease study ontology generic human disease bi-polar disorder DNA information systems manic depression UMLS |
| url | http://hdl.handle.net/20.500.11937/41098 |