Simultaneous determination of primaquine and carboxyprimaquine in plasma using solid phase extraction and LC-MS assay

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Simultaneous determination of primaquine and carboxyprimaquine in plasma using solid phase extraction and LC-MS assay

Sensitive bioanalytical methods are required for pharmacokinetic studies in children, due to the small volume and modest number of samples that can be obtained. We sought to develop a LC–MS assay for primaquine and its active metabolite, carboxyprimaquine, following simultaneous, solid phase extract...

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Bibliographic Details
Main Authors:	Page-Sharp, Madhu, Ilett, K., Betuela, I., Davis, T., Batty, Kevin
Format:	Journal Article
Published:	Elsevier 2012
Subjects:	primaquine solid phase extraction plasma carboxyprimaquine LC–MS
Online Access:	http://hdl.handle.net/20.500.11937/40766

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