New well-defined polymeric betaines: First report detailing the synthesis and ROMP of salt-responsive sulfopropylbetaine- and carboxyethylbetaine-exo-7- oxanorbornene monomers

We describe herein the synthesis and controlled ring-opening metathesis polymerization (ROMP) of highly functional zwitterionic sulfopropylbetaine- and carboxyethylbetaine-exo-7-oxanorbornene derivatives with the first-generation Grubbs' initiator RuCl 2(PCy...

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Main Authors: Rankin, D., Lowe, Andrew
Format: Journal Article
Published: American Chemical Society 2008
Online Access:http://hdl.handle.net/20.500.11937/40765
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author Rankin, D.
Lowe, Andrew
author_facet Rankin, D.
Lowe, Andrew
author_sort Rankin, D.
building Curtin Institutional Repository
collection Online Access
description We describe herein the synthesis and controlled ring-opening metathesis polymerization (ROMP) of highly functional zwitterionic sulfopropylbetaine- and carboxyethylbetaine-exo-7-oxanorbornene derivatives with the first-generation Grubbs' initiator RuCl 2(PCy 3) 2CHPh in a 2,2,2-trifluoroethanol/methylene chloride solvent mixture. These are the first examples of such norbornene-based betaine substrates. Both species can be polymerized directly in a controlled manner in organic media as judged from the kinetic profiles and aqueous size exclusion chromatographic analysis. This represents the first time betaine monomers have been polymerized directly in a controlled fashion by a technique other than a controlled free radical polymerization process, and the first time it has been achieved in organic, as opposed to aqueous, media. Finally, preliminary results demonstrate that water-soluble, salt-responsive AB diblock copolymers can be prepared and that such materials are able to undergo supramolecular self-assembly in aqueous media to yield nanosized aggregates simply by controlling the aqueous electrolyte concentration. © 2008 American Chemical Society.
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spelling curtin-20.500.11937-407652017-09-13T14:02:54Z New well-defined polymeric betaines: First report detailing the synthesis and ROMP of salt-responsive sulfopropylbetaine- and carboxyethylbetaine-exo-7- oxanorbornene monomers Rankin, D. Lowe, Andrew We describe herein the synthesis and controlled ring-opening metathesis polymerization (ROMP) of highly functional zwitterionic sulfopropylbetaine- and carboxyethylbetaine-exo-7-oxanorbornene derivatives with the first-generation Grubbs' initiator RuCl 2(PCy 3) 2CHPh in a 2,2,2-trifluoroethanol/methylene chloride solvent mixture. These are the first examples of such norbornene-based betaine substrates. Both species can be polymerized directly in a controlled manner in organic media as judged from the kinetic profiles and aqueous size exclusion chromatographic analysis. This represents the first time betaine monomers have been polymerized directly in a controlled fashion by a technique other than a controlled free radical polymerization process, and the first time it has been achieved in organic, as opposed to aqueous, media. Finally, preliminary results demonstrate that water-soluble, salt-responsive AB diblock copolymers can be prepared and that such materials are able to undergo supramolecular self-assembly in aqueous media to yield nanosized aggregates simply by controlling the aqueous electrolyte concentration. © 2008 American Chemical Society. 2008 Journal Article http://hdl.handle.net/20.500.11937/40765 10.1021/ma701952c American Chemical Society restricted
spellingShingle Rankin, D.
Lowe, Andrew
New well-defined polymeric betaines: First report detailing the synthesis and ROMP of salt-responsive sulfopropylbetaine- and carboxyethylbetaine-exo-7- oxanorbornene monomers
title New well-defined polymeric betaines: First report detailing the synthesis and ROMP of salt-responsive sulfopropylbetaine- and carboxyethylbetaine-exo-7- oxanorbornene monomers
title_full New well-defined polymeric betaines: First report detailing the synthesis and ROMP of salt-responsive sulfopropylbetaine- and carboxyethylbetaine-exo-7- oxanorbornene monomers
title_fullStr New well-defined polymeric betaines: First report detailing the synthesis and ROMP of salt-responsive sulfopropylbetaine- and carboxyethylbetaine-exo-7- oxanorbornene monomers
title_full_unstemmed New well-defined polymeric betaines: First report detailing the synthesis and ROMP of salt-responsive sulfopropylbetaine- and carboxyethylbetaine-exo-7- oxanorbornene monomers
title_short New well-defined polymeric betaines: First report detailing the synthesis and ROMP of salt-responsive sulfopropylbetaine- and carboxyethylbetaine-exo-7- oxanorbornene monomers
title_sort new well-defined polymeric betaines: first report detailing the synthesis and romp of salt-responsive sulfopropylbetaine- and carboxyethylbetaine-exo-7- oxanorbornene monomers
url http://hdl.handle.net/20.500.11937/40765