Medications used in overdose and how they are acquired – an investigation of cases attending an inner Melbourne emergency department

Objective: This study aimed to investigate which categories of medication are most commonly implicated in overdose, to compare this information with prescription data and to explore how the medications used in overdoses are typically acquired. Methods: A 12-month audit (11/2003–10/2004) of all medic...

Full description

Bibliographic Details
Main Authors: Buykx, P., Loxley, Wendy, Dietze, P., Ritter, A.
Format: Journal Article
Published: Wiley-Blackwell Publishing Asia 2010
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/4075
_version_ 1848744413173383168
author Buykx, P.
Loxley, Wendy
Dietze, P.
Ritter, A.
author_facet Buykx, P.
Loxley, Wendy
Dietze, P.
Ritter, A.
author_sort Buykx, P.
building Curtin Institutional Repository
collection Online Access
description Objective: This study aimed to investigate which categories of medication are most commonly implicated in overdose, to compare this information with prescription data and to explore how the medications used in overdoses are typically acquired. Methods: A 12-month audit (11/2003–10/2004) of all medication overdose presentations to an inner-Melbourne ED was conducted and the medications compared to published population-based prescription data. Interviews were conducted with 31 patients who attended the ED following a medication overdose and typical stories regarding the acquisition of medications reported.Results: The same broad categories of medications identified in earlier studies were found to contribute to the majority of overdoses in this study, namely benzodiazepines, antidepressants, analgesics and antipsychotics. Two benzodiazepine medications, diazepam and alprazolam, appeared to be over-represented in the overdose data relative to their population rates of prescription. Patient interviews revealed three main reasons for the original acquisition of the medications used in overdose: treatment purposes (77%); recreational use (16%); and overdose (7%). The most common source of medications (68%) used in overdose was prescription by the patient's usual doctor. Conclusion: The high representation of benzodiazepines among medications used in overdose is of ongoing concern. Implications: The time of medication prescription and dispensing may be an ideal opportunity for overdose prevention, through judicious prescribing, consideration of treatment alternatives, patient education and encouraging the safe disposal of unused medications.
first_indexed 2025-11-14T06:01:04Z
format Journal Article
id curtin-20.500.11937-4075
institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T06:01:04Z
publishDate 2010
publisher Wiley-Blackwell Publishing Asia
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-40752017-09-13T16:06:42Z Medications used in overdose and how they are acquired – an investigation of cases attending an inner Melbourne emergency department Buykx, P. Loxley, Wendy Dietze, P. Ritter, A. Overdose antidepressants emergency medicine benzodiazepines Objective: This study aimed to investigate which categories of medication are most commonly implicated in overdose, to compare this information with prescription data and to explore how the medications used in overdoses are typically acquired. Methods: A 12-month audit (11/2003–10/2004) of all medication overdose presentations to an inner-Melbourne ED was conducted and the medications compared to published population-based prescription data. Interviews were conducted with 31 patients who attended the ED following a medication overdose and typical stories regarding the acquisition of medications reported.Results: The same broad categories of medications identified in earlier studies were found to contribute to the majority of overdoses in this study, namely benzodiazepines, antidepressants, analgesics and antipsychotics. Two benzodiazepine medications, diazepam and alprazolam, appeared to be over-represented in the overdose data relative to their population rates of prescription. Patient interviews revealed three main reasons for the original acquisition of the medications used in overdose: treatment purposes (77%); recreational use (16%); and overdose (7%). The most common source of medications (68%) used in overdose was prescription by the patient's usual doctor. Conclusion: The high representation of benzodiazepines among medications used in overdose is of ongoing concern. Implications: The time of medication prescription and dispensing may be an ideal opportunity for overdose prevention, through judicious prescribing, consideration of treatment alternatives, patient education and encouraging the safe disposal of unused medications. 2010 Journal Article http://hdl.handle.net/20.500.11937/4075 10.1111/j.1753-6405.2010.00573.x Wiley-Blackwell Publishing Asia unknown
spellingShingle Overdose
antidepressants
emergency medicine
benzodiazepines
Buykx, P.
Loxley, Wendy
Dietze, P.
Ritter, A.
Medications used in overdose and how they are acquired – an investigation of cases attending an inner Melbourne emergency department
title Medications used in overdose and how they are acquired – an investigation of cases attending an inner Melbourne emergency department
title_full Medications used in overdose and how they are acquired – an investigation of cases attending an inner Melbourne emergency department
title_fullStr Medications used in overdose and how they are acquired – an investigation of cases attending an inner Melbourne emergency department
title_full_unstemmed Medications used in overdose and how they are acquired – an investigation of cases attending an inner Melbourne emergency department
title_short Medications used in overdose and how they are acquired – an investigation of cases attending an inner Melbourne emergency department
title_sort medications used in overdose and how they are acquired – an investigation of cases attending an inner melbourne emergency department
topic Overdose
antidepressants
emergency medicine
benzodiazepines
url http://hdl.handle.net/20.500.11937/4075