Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

Recent advances in next generation sequencing have made it possible to precisely characterize all somatic coding mutations that occur during the development and progression of individual cancers. Here we used these approaches to sequence the genomes (43-fold coverage) and transcriptomes of an oestro...

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Main Authors: Shah, S., Morin, R., Khattra, J., Prentice, L., Pugh, T., Burleigh, A., Delaney, A., Gelmon, K., Guliany, R., Senz, J., Steidl, C., Holt, R., Jones, S., Sun, M., Leung, G., Moore, R., Severson, T., Taylor, G., Teschendorff, A., Tse, K., Turashvili, G., Varhol, Richard, Warren, R., Watson, P., Zhao, Y., Caldas, C., Huntsman, D., Hirst, M., Marra, M., Aparicio, S.
Format: Journal Article
Published: Nature Publishing Group 2009
Online Access:http://hdl.handle.net/20.500.11937/40295

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