Designing anti-diabetic ß-cells microcapsules using polystyrenic sulfonate, polyallylamine and a tertiary bile acid: Morphology, bioenergetics and cytokine analysis.
Purpose: Recently sodium alginate (SA)-poly-l-ornithine (PLO) microcapsules containing pancreatic β-cells that showed good morphology but low cell viability (<27%) was designed. In this study, two new polyelectrolytes, polystyrenic sulfonate (PSS; at 1%) and polyallylamine (PAA; at 2%) were incor...
| Main Authors: | Mooranian, A., Negrulj, R., Morahan, G., Jamieson, E., Al-Salami, Hani |
|---|---|
| Format: | Journal Article |
| Published: |
2016
|
| Online Access: | http://hdl.handle.net/20.500.11937/40271 |
Similar Items
Primary Bile Acid Chenodeoxycholic Acid-Based Microcapsules to Examine ß-cell Survival and the Inflammatory Response
by: Mooranian, A., et al.
Published: (2016)
by: Mooranian, A., et al.
Published: (2016)
The impact of allylamine-bile acid combinations on cell delivery microcapsules in diabetes
by: Mooranian, Armin, et al.
Published: (2016)
by: Mooranian, Armin, et al.
Published: (2016)
The incorporation of water-soluble gel matrix into bile acid-based microcapsules for the delivery of viable ß-cells of the pancreas, in diabetes treatment: biocompatibility and functionality studies.
by: Mooranian, A., et al.
Published: (2015)
by: Mooranian, A., et al.
Published: (2015)
Innovative Microcapsules for Pancreatic ß-Cells Harvested from Mature Double-Transgenic Mice: Cell Imaging, Viability, Induced Glucose-Stimulated Insulin Measurements and Proinflammatory Cytokines Analysis
by: Mooranian, Armin, et al.
Published: (2017)
by: Mooranian, Armin, et al.
Published: (2017)
Viability and topographical analysis of microencapsulated ß-cells exposed to a biotransformed tertiary bile acid: An ex vivo study
by: Mooranian, Armin, et al.
Published: (2016)
by: Mooranian, Armin, et al.
Published: (2016)
New biotechnological microencapsulating methodology utilizing individualized gradient-screened jet laminar flow techniques for pancreatic ß-cell delivery: bile acids support cell energy-generating mechanisms
by: Mooranian, A., et al.
Published: (2017)
by: Mooranian, A., et al.
Published: (2017)
Influence of Biotechnological Processes, Speed of Formulation Flow and Cellular Concurrent Stream-Integration on Insulin Production from ß-cells as a Result of Co-Encapsulation with a Highly Lipophilic Bile Acid
by: Mooranian, A., et al.
Published: (2017)
by: Mooranian, A., et al.
Published: (2017)
Novel multicompartmental bile acid-based microcapsules for pancreatic β-cell transplantation
by: Mooranian, A., et al.
Published: (2015)
by: Mooranian, A., et al.
Published: (2015)
The effects of Ionic Gelation- Vibrational Jet Flow technique in fabrication of microcapsules incorporating ß-cell: applications in Type-1 Diabetes
by: Mooranian, A., et al.
Published: (2017)
by: Mooranian, A., et al.
Published: (2017)
Characterization of a novel bile acid-based delivery platform for microencapsulated pancreatic ß-cells.
by: Mooranian, Armin, et al.
Published: (2014)
by: Mooranian, Armin, et al.
Published: (2014)
Flow vibration-doubled concentric system coupled with low ratio amine to produce bile acid-macrocapsules of ß-cells
by: Mooranian, Armin, et al.
Published: (2016)
by: Mooranian, Armin, et al.
Published: (2016)
Biological Assessments of Encapsulated Pancreatic ß-Cells: Their Potential Transplantation in Diabetes
by: Mooranian, Armin, et al.
Published: (2016)
by: Mooranian, Armin, et al.
Published: (2016)
NOVEL MULTICOMPARTMENTAL BILE ACID-BASED MICROCAPSULES FOR PANCREATIC beta-CELL TRANSPLANTATION
by: Mooranian, A., et al.
Published: (2015)
by: Mooranian, A., et al.
Published: (2015)
Electrokinetic potential-stabilization by bile acid-microencapsulating formulation of pancreatic ß-cells cultured in high ratio poly-L-ornithine-gel hydrogel colloidal dispersion: applications in cell-biomaterials, tissue engineering and biotechnological applications
by: Mooranian, A., et al.
Published: (2017)
by: Mooranian, A., et al.
Published: (2017)
Morphological, Stability, and Hypoglycemic Effects of New Gliclazide-Bile Acid Microcapsules for Type 1 Diabetes Treatment: the Microencapsulation of Anti-diabetics Using a Microcapsule-Stabilizing Bile Acid
by: Mathavan, S., et al.
Published: (2018)
by: Mathavan, S., et al.
Published: (2018)
The effect of a tertiary bile acid, taurocholic acid, on the morphology and physical characteristics of microencapsulated probucol: potential applications in diabetes: a characterization study
by: Mooranian, A., et al.
Published: (2015)
by: Mooranian, A., et al.
Published: (2015)
Eudragit®-based microcapsules of probucol with a gut-bacterial processed secondary bile acid
by: Mooranian, A., et al.
Published: (2018)
by: Mooranian, A., et al.
Published: (2018)
Alginate-combined cholic acid increased insulin secretion of microencapsulated mouse cloned pancreatic ß cells
by: Mooranian, A., et al.
Published: (2017)
by: Mooranian, A., et al.
Published: (2017)
Multicompartmental, multilayered probucol microcapsules for diabetes mellitus: Formulation characterization and effects on production of insulin and inflammation in a pancreatic ß-cell line
by: Mooranian, A., et al.
Published: (2015)
by: Mooranian, A., et al.
Published: (2015)
Advanced bile acid-based multi-compartmental microencapsulated pancreatic ß-cells integrating a polyelectrolyte-bile acid formulation, for diabetes treatment.
by: Mooranian, A., et al.
Published: (2014)
by: Mooranian, A., et al.
Published: (2014)
Swelling, mechanical strength, and release properties of probucol microcapsules with and without a bile acid, and their potential oral delivery in diabetes
by: Negrulj, R., et al.
Published: (2015)
by: Negrulj, R., et al.
Published: (2015)
Potentials and Limitations of Bile Acids in Type 2 Diabetes Mellitus: Applications of Microencapsulation as a Novel Oral Delivery System
by: Negrulj, Rebecca, et al.
Published: (2013)
by: Negrulj, Rebecca, et al.
Published: (2013)
The effect of molecular weights of microencapsulating polymers on viability of mouse-cloned pancreatic ß-cells: biomaterials, osmotic forces and potential applications in diabetes treatment
by: Mooranian, A., et al.
Published: (2018)
by: Mooranian, A., et al.
Published: (2018)
A comprehensive study of novel microcapsules incorporating gliclazide and a permeation enhancing bile acid: hypoglycemic effect in an animal model of Type-1 diabetes
by: Mathavan, Sangeetha, et al.
Published: (2015)
by: Mathavan, Sangeetha, et al.
Published: (2015)
An optimized probucol microencapsulated formulation integrating a secondary bile acid (deoxycholic acid) as a permeation enhancer
by: Mooranian, Armin, et al.
Published: (2014)
by: Mooranian, Armin, et al.
Published: (2014)
The biological effects of the hypolipidaemic drug probucol microcapsules fed daily for 4 weeks, to an insulin-resistant mouse model: potential hypoglycaemic and anti-inflammatory effects
by: Mooranian, Armin, et al.
Published: (2018)
by: Mooranian, Armin, et al.
Published: (2018)
Esterification of Acrylic Acid with Butanol to Butyl Acrylate over Sulfonated Polystyrene
by: Chin, S. Y., et al.
Published: (2014)
by: Chin, S. Y., et al.
Published: (2014)
Probucol Release from Novel Multicompartmental Microcapsules for the Oral Targeted Delivery in Type 2 Diabetes
by: Mooranian, Armin, et al.
Published: (2014)
by: Mooranian, Armin, et al.
Published: (2014)
Release and swelling studies of an innovative antidiabetic-bile acid microencapsulated formulation, as a novel targeted therapy for diabetes treatment
by: Mooranian, Armin, et al.
Published: (2015)
by: Mooranian, Armin, et al.
Published: (2015)
XPS studies of radiation grafted PTFE-g-polystyrene sulfonic acid membranes
by: Nasef, Mohamed Mahmoud, et al.
Published: (2000)
by: Nasef, Mohamed Mahmoud, et al.
Published: (2000)
Novel artificial cell microencapsulation of probucol and bile acids in diabetes mellitus
by: Mooranian, Armin
Published: (2018)
by: Mooranian, Armin
Published: (2018)
Bile acids and probiotics could help treating diabetes
by: Calasan, J., et al.
Published: (2012)
by: Calasan, J., et al.
Published: (2012)
The role of vitamin D status in the bioenergetics of inflammation
by: Calton, Emily Kathleen
Published: (2017)
by: Calton, Emily Kathleen
Published: (2017)
An advanced microencapsulated system: a platform for optimized oral delivery of antidiabetic drug-bile acid formulations
by: Mooranian, A., et al.
Published: (2015)
by: Mooranian, A., et al.
Published: (2015)
Novel artificial cell microencapsulation of a complex gliclazide-deoxycholic bile acid formulation: A Characterization Study
by: Mooranian, Armin, et al.
Published: (2014)
by: Mooranian, Armin, et al.
Published: (2014)
Pharmacokinetic and Drug Absorption Profiles of the Anti-Hyperglycaemic Agent Gliclazide in Oral Tissue-Targeted Microcapsules in Rats
by: Jovic, Jelena, et al.
Published: (2020)
by: Jovic, Jelena, et al.
Published: (2020)
Chemical Equilibrium and kinetic study of the esterification of acrylic acid with butanol catalysed by sulfonated expanded polystyrene
by: Muhammad Ridzuan, Kamaruzaman
Published: (2015)
by: Muhammad Ridzuan, Kamaruzaman
Published: (2015)
Characterization of Sulfonated, Radiation-Induced Polystyrene-Grafted Fluorinated Base Polymer Proton Exchange Membranes
by: Hussain, Muhammad Yousuf
Published: (2007)
by: Hussain, Muhammad Yousuf
Published: (2007)
Physico-chemical study of sulfonated polystyrene pore-filled electrolyte membranes by electrons induced grafting
by: Zubir, N. A., et al.
Published: (2004)
by: Zubir, N. A., et al.
Published: (2004)
Physico-chemical study of sulfonated polystyrene pore-filled electrolyte membranes by electrons induced grafting
by: Ismail, A. F., et al.
Published: (2005)
by: Ismail, A. F., et al.
Published: (2005)
Similar Items
-
Primary Bile Acid Chenodeoxycholic Acid-Based Microcapsules to Examine ß-cell Survival and the Inflammatory Response
by: Mooranian, A., et al.
Published: (2016) -
The impact of allylamine-bile acid combinations on cell delivery microcapsules in diabetes
by: Mooranian, Armin, et al.
Published: (2016) -
The incorporation of water-soluble gel matrix into bile acid-based microcapsules for the delivery of viable ß-cells of the pancreas, in diabetes treatment: biocompatibility and functionality studies.
by: Mooranian, A., et al.
Published: (2015) -
Innovative Microcapsules for Pancreatic ß-Cells Harvested from Mature Double-Transgenic Mice: Cell Imaging, Viability, Induced Glucose-Stimulated Insulin Measurements and Proinflammatory Cytokines Analysis
by: Mooranian, Armin, et al.
Published: (2017) -
Viability and topographical analysis of microencapsulated ß-cells exposed to a biotransformed tertiary bile acid: An ex vivo study
by: Mooranian, Armin, et al.
Published: (2016)