Patient characteristics differently affect early cup and stem loosening in THA: A case-control study on 7,535 patients

We postulated that certain patient characteristics have different effects on early THA component loosening. With two matched case-control studies we assessed 3,028 cups and 5,224 stems. Loosening was defined using signs of mechanical component failure on routine follow-up radiographs or revision for...

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Main Authors: Röder, C., Eggli, S., Münger, P., Melloh, Markus, Busato, A.
Format: Journal Article
Published: 2008
Online Access:http://hdl.handle.net/20.500.11937/39782
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author Röder, C.
Eggli, S.
Münger, P.
Melloh, Markus
Busato, A.
author_facet Röder, C.
Eggli, S.
Münger, P.
Melloh, Markus
Busato, A.
author_sort Röder, C.
building Curtin Institutional Repository
collection Online Access
description We postulated that certain patient characteristics have different effects on early THA component loosening. With two matched case-control studies we assessed 3,028 cups and 5,224 stems. Loosening was defined using signs of mechanical component failure on routine follow-up radiographs or revision for aseptic loosening. Women and men had similar cup-loosening odds, but women had lower odds for stem loosening (p<0.0001). Odds for cup loosening decreased by 2.1% per additional year of age (p=0.0004), those for stem loosening by 2.4% (p<0.0001). Each additional kilogram of weight decreased cup loosening odds by 1.3% (p=0.0051). Each additional unit of BMI increased stem loosening odds (p=0.0109). Charnley classes B and C were protective factors against loosening of both components. There were no risk differences for the various main diagnoses. Certain patient characteristics differently affected early cup and stem loosening, although some characteristics had the same protective or harmful effect on component survival. © 2007 Springer-Verlag.
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spelling curtin-20.500.11937-397822018-03-29T09:07:46Z Patient characteristics differently affect early cup and stem loosening in THA: A case-control study on 7,535 patients Röder, C. Eggli, S. Münger, P. Melloh, Markus Busato, A. We postulated that certain patient characteristics have different effects on early THA component loosening. With two matched case-control studies we assessed 3,028 cups and 5,224 stems. Loosening was defined using signs of mechanical component failure on routine follow-up radiographs or revision for aseptic loosening. Women and men had similar cup-loosening odds, but women had lower odds for stem loosening (p<0.0001). Odds for cup loosening decreased by 2.1% per additional year of age (p=0.0004), those for stem loosening by 2.4% (p<0.0001). Each additional kilogram of weight decreased cup loosening odds by 1.3% (p=0.0051). Each additional unit of BMI increased stem loosening odds (p=0.0109). Charnley classes B and C were protective factors against loosening of both components. There were no risk differences for the various main diagnoses. Certain patient characteristics differently affected early cup and stem loosening, although some characteristics had the same protective or harmful effect on component survival. © 2007 Springer-Verlag. 2008 Journal Article http://hdl.handle.net/20.500.11937/39782 10.1007/s00264-006-0291-8 restricted
spellingShingle Röder, C.
Eggli, S.
Münger, P.
Melloh, Markus
Busato, A.
Patient characteristics differently affect early cup and stem loosening in THA: A case-control study on 7,535 patients
title Patient characteristics differently affect early cup and stem loosening in THA: A case-control study on 7,535 patients
title_full Patient characteristics differently affect early cup and stem loosening in THA: A case-control study on 7,535 patients
title_fullStr Patient characteristics differently affect early cup and stem loosening in THA: A case-control study on 7,535 patients
title_full_unstemmed Patient characteristics differently affect early cup and stem loosening in THA: A case-control study on 7,535 patients
title_short Patient characteristics differently affect early cup and stem loosening in THA: A case-control study on 7,535 patients
title_sort patient characteristics differently affect early cup and stem loosening in tha: a case-control study on 7,535 patients
url http://hdl.handle.net/20.500.11937/39782