Antibody Recognition of Cancer-Related Gangliosides and Their Mimics Investigated Using in silico Site Mapping

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Antibody Recognition of Cancer-Related Gangliosides and Their Mimics Investigated Using in silico Site Mapping

Modified gangliosides may be overexpressed in certain types of cancer, thus, they are considered a valuable target in cancer immunotherapy. Structural knowledge of their interaction with antibodies is currently limited, due to the large size and high flexibility of these ligands. In this study, we a...

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Bibliographic Details
Main Authors:	Agostino, Mark, Yuriev, E., Ramsland, Paul
Format:	Journal Article
Published:	Public Library of Science 2012
Online Access:	http://hdl.handle.net/20.500.11937/39513

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