Psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder: results of the IASP study
Aims To determine comorbidity patterns in treatment-seeking substance use disorder (SUD) patients with and without adult attention deficit hyperactivity disorder (ADHD), with an emphasis on subgroups defined by ADHD subtype, taking into account differences related to gender and primary substance o...
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| Format: | Journal Article |
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Wiley-Blackwell Publishing Ltd.
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/39443 |
| _version_ | 1848755592284340224 |
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| author | Van Emmerik-Van Oortmerssen, K. Van de Glind, G. Koeter, M. Allsop, Steve Auriacombe, M. Barta, C. Bu, E. Burren, Y. Carpentier, P. Carruthers, Susan Casas, M. Demetrovics, Z. Dom, G. Faraone, S. Fatséas, M. Franck, J. Johnson, B. Kapitány-Fövény, M. Kaye, S. Konstenius, M. Levin, F. Moggi, F. Møller, M. Ramos-Quiroga, J. Schillinger, A. Skutle, A. Verspreet, S. Van Den Brink, W. Schoevers, R. |
| author_facet | Van Emmerik-Van Oortmerssen, K. Van de Glind, G. Koeter, M. Allsop, Steve Auriacombe, M. Barta, C. Bu, E. Burren, Y. Carpentier, P. Carruthers, Susan Casas, M. Demetrovics, Z. Dom, G. Faraone, S. Fatséas, M. Franck, J. Johnson, B. Kapitány-Fövény, M. Kaye, S. Konstenius, M. Levin, F. Moggi, F. Møller, M. Ramos-Quiroga, J. Schillinger, A. Skutle, A. Verspreet, S. Van Den Brink, W. Schoevers, R. |
| author_sort | Van Emmerik-Van Oortmerssen, K. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Aims To determine comorbidity patterns in treatment-seeking substance use disorder (SUD) patients with and without adult attention deficit hyperactivity disorder (ADHD), with an emphasis on subgroups defined by ADHD subtype, taking into account differences related to gender and primary substance of abuse. Design Data were obtained from the cross-sectional International ADHD in Substance use disorder Prevalence (IASP) study. Setting Forty-seven centres of SUD treatment in 10 countries. Participants A total of 1205 treatment-seeking SUD patients. Measurements Structured diagnostic assessments were used for all disorders: presence of ADHD was assessed with the Conners’ Adult ADHD Diagnostic Interview for DSM-IV (CAADID), the presence of antisocial personality disorder (ASPD), major depression (MD) and (hypo)manic episode (HME) was assessed with the Mini International Neuropsychiatric Interview-Plus (MINI Plus), and the presence of borderline personality disorder (BPD) was assessed with the Structured Clinical Interview for DSM-IV Axis II (SCID II). Findings The prevalence of DSM-IV adult ADHD in this SUD sample was 13.9%. ASPD [odds ratio (OR) = 2.8, 95% confidence interval (CI) = 1.8–4.2], BPD (OR = 7.0, 95% CI = 3.1–15.6 for alcohol; OR = 3.4, 95% CI = 1.8–6.4 for drugs), MD in patients with alcohol as primary substance of abuse (OR = 4.1, 95% CI = 2.1–7.8) andHME(OR = 4.3, 95% CI = 2.1–8.7)were all more prevalent in ADHD+ compared with ADHD- patients (P < 0.001). These results also indicate increased levels of BPD and MD for alcohol compared with drugs as primary substance of abuse. Comorbidity patterns differed between ADHD subtypes with increased MD in the inattentive and combined subtype (P < 0.01), increased HME and ASPD in the hyperactive/impulsive (P < 0.01) and combined subtypes (P < 0.001) and increased BPD in all subtypes (P < 0.001) compared with SUD patients without ADHD. Seventy-five per cent of ADHD patients had at least one additional comorbid disorder compared with 37% of SUD patients without ADHD. Conclusions Treatment-seeking substance use disorder patients with attention deficit hyperactivity disorder are at a very high risk for additional externalizing disorders. |
| first_indexed | 2025-11-14T08:58:45Z |
| format | Journal Article |
| id | curtin-20.500.11937-39443 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:58:45Z |
| publishDate | 2014 |
| publisher | Wiley-Blackwell Publishing Ltd. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-394432018-03-29T09:07:45Z Psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder: results of the IASP study Van Emmerik-Van Oortmerssen, K. Van de Glind, G. Koeter, M. Allsop, Steve Auriacombe, M. Barta, C. Bu, E. Burren, Y. Carpentier, P. Carruthers, Susan Casas, M. Demetrovics, Z. Dom, G. Faraone, S. Fatséas, M. Franck, J. Johnson, B. Kapitány-Fövény, M. Kaye, S. Konstenius, M. Levin, F. Moggi, F. Møller, M. Ramos-Quiroga, J. Schillinger, A. Skutle, A. Verspreet, S. Van Den Brink, W. Schoevers, R. - depression comorbidity ADHD bipolar disorder antisocial personality disorder borderline personality disorder substance use disorder Aims To determine comorbidity patterns in treatment-seeking substance use disorder (SUD) patients with and without adult attention deficit hyperactivity disorder (ADHD), with an emphasis on subgroups defined by ADHD subtype, taking into account differences related to gender and primary substance of abuse. Design Data were obtained from the cross-sectional International ADHD in Substance use disorder Prevalence (IASP) study. Setting Forty-seven centres of SUD treatment in 10 countries. Participants A total of 1205 treatment-seeking SUD patients. Measurements Structured diagnostic assessments were used for all disorders: presence of ADHD was assessed with the Conners’ Adult ADHD Diagnostic Interview for DSM-IV (CAADID), the presence of antisocial personality disorder (ASPD), major depression (MD) and (hypo)manic episode (HME) was assessed with the Mini International Neuropsychiatric Interview-Plus (MINI Plus), and the presence of borderline personality disorder (BPD) was assessed with the Structured Clinical Interview for DSM-IV Axis II (SCID II). Findings The prevalence of DSM-IV adult ADHD in this SUD sample was 13.9%. ASPD [odds ratio (OR) = 2.8, 95% confidence interval (CI) = 1.8–4.2], BPD (OR = 7.0, 95% CI = 3.1–15.6 for alcohol; OR = 3.4, 95% CI = 1.8–6.4 for drugs), MD in patients with alcohol as primary substance of abuse (OR = 4.1, 95% CI = 2.1–7.8) andHME(OR = 4.3, 95% CI = 2.1–8.7)were all more prevalent in ADHD+ compared with ADHD- patients (P < 0.001). These results also indicate increased levels of BPD and MD for alcohol compared with drugs as primary substance of abuse. Comorbidity patterns differed between ADHD subtypes with increased MD in the inattentive and combined subtype (P < 0.01), increased HME and ASPD in the hyperactive/impulsive (P < 0.01) and combined subtypes (P < 0.001) and increased BPD in all subtypes (P < 0.001) compared with SUD patients without ADHD. Seventy-five per cent of ADHD patients had at least one additional comorbid disorder compared with 37% of SUD patients without ADHD. Conclusions Treatment-seeking substance use disorder patients with attention deficit hyperactivity disorder are at a very high risk for additional externalizing disorders. 2014 Journal Article http://hdl.handle.net/20.500.11937/39443 10.1016/j.drugalcdep.2013.04.010 Wiley-Blackwell Publishing Ltd. restricted |
| spellingShingle | - depression comorbidity ADHD bipolar disorder antisocial personality disorder borderline personality disorder substance use disorder Van Emmerik-Van Oortmerssen, K. Van de Glind, G. Koeter, M. Allsop, Steve Auriacombe, M. Barta, C. Bu, E. Burren, Y. Carpentier, P. Carruthers, Susan Casas, M. Demetrovics, Z. Dom, G. Faraone, S. Fatséas, M. Franck, J. Johnson, B. Kapitány-Fövény, M. Kaye, S. Konstenius, M. Levin, F. Moggi, F. Møller, M. Ramos-Quiroga, J. Schillinger, A. Skutle, A. Verspreet, S. Van Den Brink, W. Schoevers, R. Psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder: results of the IASP study |
| title | Psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder: results of the IASP study |
| title_full | Psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder: results of the IASP study |
| title_fullStr | Psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder: results of the IASP study |
| title_full_unstemmed | Psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder: results of the IASP study |
| title_short | Psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder: results of the IASP study |
| title_sort | psychiatric comorbidity in treatment-seeking substance use disorder patients with and without attention deficit hyperactivity disorder: results of the iasp study |
| topic | - depression comorbidity ADHD bipolar disorder antisocial personality disorder borderline personality disorder substance use disorder |
| url | http://hdl.handle.net/20.500.11937/39443 |