Syringomyelia and the fluid-structure interactions of a cerebrospinal waveguide

In the disease syringomyelia, fluid-filled cavities, called syrinxes, form in the spinal cord. The expansion of these pathological pressure vessels compresses the surrounding nerve fibers and blood supply, which is associated with neurological damage. We investigate the spinal wave-propagation chara...

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Main Authors: Elliott, N., Lucey, Anthony, Lockerby, D., Brodbelt, A.
Format: Conference Paper
Published: 2014
Online Access:http://hdl.handle.net/20.500.11937/39418
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author Elliott, N.
Lucey, Anthony
Lockerby, D.
Brodbelt, A.
author_facet Elliott, N.
Lucey, Anthony
Lockerby, D.
Brodbelt, A.
author_sort Elliott, N.
building Curtin Institutional Repository
collection Online Access
description In the disease syringomyelia, fluid-filled cavities, called syrinxes, form in the spinal cord. The expansion of these pathological pressure vessels compresses the surrounding nerve fibers and blood supply, which is associated with neurological damage. We investigate the spinal wave-propagation characteristics, principally to serve as a reference for more anatomically-detailed models. The spinal cord is modeled as an elastic cylinder, which becomes an annulus containing inviscid fluid when a syrinx is included. This is surrounded by an annulus of in-viscid fluid, representing the cerebrospinal fluid occupying the subarachnoid space, with an outer rigid boundary approximating the dura mater. The axisymmetric harmonic motion is solved as an eigenvalue problem. We present dispersion diagrams and describe the physical mechanism of each wave mode. We identify potentially damaging syrinx fluid motions and tissue stress concentrations from the eigenvectors. Finally, we determine the dependence of each wave mode on syrinx radius and cord tissue compressibility.
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spelling curtin-20.500.11937-394182017-09-13T14:26:11Z Syringomyelia and the fluid-structure interactions of a cerebrospinal waveguide Elliott, N. Lucey, Anthony Lockerby, D. Brodbelt, A. In the disease syringomyelia, fluid-filled cavities, called syrinxes, form in the spinal cord. The expansion of these pathological pressure vessels compresses the surrounding nerve fibers and blood supply, which is associated with neurological damage. We investigate the spinal wave-propagation characteristics, principally to serve as a reference for more anatomically-detailed models. The spinal cord is modeled as an elastic cylinder, which becomes an annulus containing inviscid fluid when a syrinx is included. This is surrounded by an annulus of in-viscid fluid, representing the cerebrospinal fluid occupying the subarachnoid space, with an outer rigid boundary approximating the dura mater. The axisymmetric harmonic motion is solved as an eigenvalue problem. We present dispersion diagrams and describe the physical mechanism of each wave mode. We identify potentially damaging syrinx fluid motions and tissue stress concentrations from the eigenvectors. Finally, we determine the dependence of each wave mode on syrinx radius and cord tissue compressibility. 2014 Conference Paper http://hdl.handle.net/20.500.11937/39418 10.1115/PVP2014-29095 restricted
spellingShingle Elliott, N.
Lucey, Anthony
Lockerby, D.
Brodbelt, A.
Syringomyelia and the fluid-structure interactions of a cerebrospinal waveguide
title Syringomyelia and the fluid-structure interactions of a cerebrospinal waveguide
title_full Syringomyelia and the fluid-structure interactions of a cerebrospinal waveguide
title_fullStr Syringomyelia and the fluid-structure interactions of a cerebrospinal waveguide
title_full_unstemmed Syringomyelia and the fluid-structure interactions of a cerebrospinal waveguide
title_short Syringomyelia and the fluid-structure interactions of a cerebrospinal waveguide
title_sort syringomyelia and the fluid-structure interactions of a cerebrospinal waveguide
url http://hdl.handle.net/20.500.11937/39418