Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes
Background: A significant proportion of individuals taking antihypertensive therapies fail to achieve blood pressures <140/90mmHg. In order to develop strategies for improved treatment of blood pressure, we examined the association of blood pressure control with antihypertensive therapies and...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal Article |
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2013
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| Online Access: | http://hdl.handle.net/20.500.11937/39312 |
| _version_ | 1848755557152849920 |
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| author | Campbell, D. Mcgrady, M. Prior, D. Coller, J. Boffa, U. Shiel, L. Liew, D. Wolfe, R. Stewart, S. Reid, Christopher Krum, H. |
| author_facet | Campbell, D. Mcgrady, M. Prior, D. Coller, J. Boffa, U. Shiel, L. Liew, D. Wolfe, R. Stewart, S. Reid, Christopher Krum, H. |
| author_sort | Campbell, D. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background: A significant proportion of individuals taking antihypertensive therapies fail to achieve blood pressures <140/90mmHg. In order to develop strategies for improved treatment of blood pressure, we examined the association of blood pressure control with antihypertensive therapies and clinical and lifestyle factors in a cohort of adults at increased cardiovascular risk. Methods: A cross-sectional study of 3994 adults from Melbourne and Shepparton, Australia enrolled in the SCReening Evaluation of the Evolution of New Heart Failure (SCREEN-HF) study. Inclusion criteria were age =60 years with one or more of self-reported ischaemic or other heart disease, atrial fibrillation, cerebrovascular disease, renal impairment or treatment for hypertension or diabetes for =2 years. Exclusion criteria were known heart failure or cardiac abnormality on echocardiography or other imaging. The main outcome measures were the proportion of participants receiving antihypertensive therapy with blood pressures =140/90mmHg and the association of blood pressure control with antihypertensive therapies and clinical and lifestyle factors. Results: Of 3623 participants (1975 men and 1648 women) receiving antihypertensive therapy, 1867 (52%) had blood pressures =140/90mmHg. Of these 1867 participants, 1483 (79%) were receiving only one or two antihypertensive drug classes. Blood pressures =140/90mmHg were associated with increased age, male sex, waist circumference and log amino-terminal-pro-B-type natriuretic peptide levels. Conclusions: Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes. Prescribing additional antihypertensive drug classes and lifestyle modification may improve blood pressure control in this population of individuals at increased cardiovascular risk. © 2012 The Authors. Internal Medicine Journal © 2012 Royal Australasian College of Physicians. |
| first_indexed | 2025-11-14T08:58:12Z |
| format | Journal Article |
| id | curtin-20.500.11937-39312 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:58:12Z |
| publishDate | 2013 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-393122017-09-13T14:23:35Z Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes Campbell, D. Mcgrady, M. Prior, D. Coller, J. Boffa, U. Shiel, L. Liew, D. Wolfe, R. Stewart, S. Reid, Christopher Krum, H. Background: A significant proportion of individuals taking antihypertensive therapies fail to achieve blood pressures <140/90mmHg. In order to develop strategies for improved treatment of blood pressure, we examined the association of blood pressure control with antihypertensive therapies and clinical and lifestyle factors in a cohort of adults at increased cardiovascular risk. Methods: A cross-sectional study of 3994 adults from Melbourne and Shepparton, Australia enrolled in the SCReening Evaluation of the Evolution of New Heart Failure (SCREEN-HF) study. Inclusion criteria were age =60 years with one or more of self-reported ischaemic or other heart disease, atrial fibrillation, cerebrovascular disease, renal impairment or treatment for hypertension or diabetes for =2 years. Exclusion criteria were known heart failure or cardiac abnormality on echocardiography or other imaging. The main outcome measures were the proportion of participants receiving antihypertensive therapy with blood pressures =140/90mmHg and the association of blood pressure control with antihypertensive therapies and clinical and lifestyle factors. Results: Of 3623 participants (1975 men and 1648 women) receiving antihypertensive therapy, 1867 (52%) had blood pressures =140/90mmHg. Of these 1867 participants, 1483 (79%) were receiving only one or two antihypertensive drug classes. Blood pressures =140/90mmHg were associated with increased age, male sex, waist circumference and log amino-terminal-pro-B-type natriuretic peptide levels. Conclusions: Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes. Prescribing additional antihypertensive drug classes and lifestyle modification may improve blood pressure control in this population of individuals at increased cardiovascular risk. © 2012 The Authors. Internal Medicine Journal © 2012 Royal Australasian College of Physicians. 2013 Journal Article http://hdl.handle.net/20.500.11937/39312 10.1111/j.1445-5994.2012.02927.x restricted |
| spellingShingle | Campbell, D. Mcgrady, M. Prior, D. Coller, J. Boffa, U. Shiel, L. Liew, D. Wolfe, R. Stewart, S. Reid, Christopher Krum, H. Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes |
| title | Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes |
| title_full | Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes |
| title_fullStr | Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes |
| title_full_unstemmed | Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes |
| title_short | Most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes |
| title_sort | most individuals with treated blood pressures above target receive only one or two antihypertensive drug classes |
| url | http://hdl.handle.net/20.500.11937/39312 |