Age-related changes in short-interval intracortical facilitation and dexterity
Functional changes in the primary motor cortex might contribute to the age-related decline infine motor control. We measured short-interval intracortical facilitation (SICF) in an intrinsichand muscle with paired-pulse transcranial magnetic stimulation at interstimulus intervals(ISIs) of 1.5, 2.5, a...
| Main Authors: | , , |
|---|---|
| Format: | Journal Article |
| Published: |
Lippincott Williams & Wilkins
2011
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/39178 |
| _version_ | 1848755520715882496 |
|---|---|
| author | Clark, J. Loftus, Andrea Hammond, G. |
| author_facet | Clark, J. Loftus, Andrea Hammond, G. |
| author_sort | Clark, J. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Functional changes in the primary motor cortex might contribute to the age-related decline infine motor control. We measured short-interval intracortical facilitation (SICF) in an intrinsichand muscle with paired-pulse transcranial magnetic stimulation at interstimulus intervals(ISIs) of 1.5, 2.5, and 4.5 ms in young and old subjects and examined its association withdexterity. We found age-related effects in SICF, with greater facilitation in old than youngsubjects at the 1.5-ms ISI and greater facilitation in young than old subjects at the 2.5-ms ISI.SICF at the 2.5-ms ISI was positively correlated with performance on a task that requiredcoordinated and dextrous use of both hands, suggesting that this measure indicates a capacityfor executing demanding manual tasks. |
| first_indexed | 2025-11-14T08:57:37Z |
| format | Journal Article |
| id | curtin-20.500.11937-39178 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:57:37Z |
| publishDate | 2011 |
| publisher | Lippincott Williams & Wilkins |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-391782017-01-30T14:31:20Z Age-related changes in short-interval intracortical facilitation and dexterity Clark, J. Loftus, Andrea Hammond, G. manual dexterity motor control TMS ageing SICF motor cortex aging Functional changes in the primary motor cortex might contribute to the age-related decline infine motor control. We measured short-interval intracortical facilitation (SICF) in an intrinsichand muscle with paired-pulse transcranial magnetic stimulation at interstimulus intervals(ISIs) of 1.5, 2.5, and 4.5 ms in young and old subjects and examined its association withdexterity. We found age-related effects in SICF, with greater facilitation in old than youngsubjects at the 1.5-ms ISI and greater facilitation in young than old subjects at the 2.5-ms ISI.SICF at the 2.5-ms ISI was positively correlated with performance on a task that requiredcoordinated and dextrous use of both hands, suggesting that this measure indicates a capacityfor executing demanding manual tasks. 2011 Journal Article http://hdl.handle.net/20.500.11937/39178 Lippincott Williams & Wilkins fulltext |
| spellingShingle | manual dexterity motor control TMS ageing SICF motor cortex aging Clark, J. Loftus, Andrea Hammond, G. Age-related changes in short-interval intracortical facilitation and dexterity |
| title | Age-related changes in short-interval intracortical facilitation and dexterity |
| title_full | Age-related changes in short-interval intracortical facilitation and dexterity |
| title_fullStr | Age-related changes in short-interval intracortical facilitation and dexterity |
| title_full_unstemmed | Age-related changes in short-interval intracortical facilitation and dexterity |
| title_short | Age-related changes in short-interval intracortical facilitation and dexterity |
| title_sort | age-related changes in short-interval intracortical facilitation and dexterity |
| topic | manual dexterity motor control TMS ageing SICF motor cortex aging |
| url | http://hdl.handle.net/20.500.11937/39178 |