Strategies to Achieve Control over the Surface Ratio of Two Different Components on Modified Electrodes Using Aryldiazonium Salts
Controlling the composition of an interface is very important in tuning the chemical and physical properties of a surface in many applications including biosensors, biomaterials, and chemical catalysis. Frequently, this requires one molecular component to a minor component in a mixed layer. Such sub...
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| Format: | Journal Article |
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American Chemical Society
2016
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| Online Access: | http://purl.org/au-research/grants/arc/CE140100036 http://hdl.handle.net/20.500.11937/39085 |
| _version_ | 1848755495043596288 |
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| author | Jiang, C. Alam, M. Parker, S. Darwish, Nadim Gooding, J. |
| author_facet | Jiang, C. Alam, M. Parker, S. Darwish, Nadim Gooding, J. |
| author_sort | Jiang, C. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Controlling the composition of an interface is very important in tuning the chemical and physical properties of a surface in many applications including biosensors, biomaterials, and chemical catalysis. Frequently, this requires one molecular component to a minor component in a mixed layer. Such subtle control of composition has been difficult to achieve using aryldiazonium salts. Herein, aryldiazonium salts of carboxyphenyl (CP) and phenylphosphorylcholine (PPC), generated in situ from their corresponding anilines, are electrografted to form molecular platform that are available for further functionalization. These two components are chosen because CP provides a convenient functionality for further coupling of biorecognition species while PPC offers resistance to nonspecific adsorption of proteins to the surface. Mixed layers of CP and PPC were prepared by grafting them either simultaneously or consecutively. The latter strategy allows an interface to be developed in a controlled way where one component is at levels of less than 1% of the total layer. |
| first_indexed | 2025-11-14T08:57:12Z |
| format | Journal Article |
| id | curtin-20.500.11937-39085 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:57:12Z |
| publishDate | 2016 |
| publisher | American Chemical Society |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-390852017-09-13T14:22:50Z Strategies to Achieve Control over the Surface Ratio of Two Different Components on Modified Electrodes Using Aryldiazonium Salts Jiang, C. Alam, M. Parker, S. Darwish, Nadim Gooding, J. Controlling the composition of an interface is very important in tuning the chemical and physical properties of a surface in many applications including biosensors, biomaterials, and chemical catalysis. Frequently, this requires one molecular component to a minor component in a mixed layer. Such subtle control of composition has been difficult to achieve using aryldiazonium salts. Herein, aryldiazonium salts of carboxyphenyl (CP) and phenylphosphorylcholine (PPC), generated in situ from their corresponding anilines, are electrografted to form molecular platform that are available for further functionalization. These two components are chosen because CP provides a convenient functionality for further coupling of biorecognition species while PPC offers resistance to nonspecific adsorption of proteins to the surface. Mixed layers of CP and PPC were prepared by grafting them either simultaneously or consecutively. The latter strategy allows an interface to be developed in a controlled way where one component is at levels of less than 1% of the total layer. 2016 Journal Article http://hdl.handle.net/20.500.11937/39085 10.1021/acs.langmuir.5b04550 http://purl.org/au-research/grants/arc/CE140100036 American Chemical Society fulltext |
| spellingShingle | Jiang, C. Alam, M. Parker, S. Darwish, Nadim Gooding, J. Strategies to Achieve Control over the Surface Ratio of Two Different Components on Modified Electrodes Using Aryldiazonium Salts |
| title | Strategies to Achieve Control over the Surface Ratio of Two Different Components on Modified Electrodes Using Aryldiazonium Salts |
| title_full | Strategies to Achieve Control over the Surface Ratio of Two Different Components on Modified Electrodes Using Aryldiazonium Salts |
| title_fullStr | Strategies to Achieve Control over the Surface Ratio of Two Different Components on Modified Electrodes Using Aryldiazonium Salts |
| title_full_unstemmed | Strategies to Achieve Control over the Surface Ratio of Two Different Components on Modified Electrodes Using Aryldiazonium Salts |
| title_short | Strategies to Achieve Control over the Surface Ratio of Two Different Components on Modified Electrodes Using Aryldiazonium Salts |
| title_sort | strategies to achieve control over the surface ratio of two different components on modified electrodes using aryldiazonium salts |
| url | http://purl.org/au-research/grants/arc/CE140100036 http://hdl.handle.net/20.500.11937/39085 |