Readmission to intensive care: development of a nomogram for individualising risk

Background: Readmission to intensive care during the same hospital stay has been associated with a greater risk of in-hospital mortality and has been suggested as a marker ofquality of care. There is lack of published research attempting to develop clinical prediction tools that individualise the ri...

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Main Authors: Frost, S., Tam, V., Alexandrou, Evan, Hunt, L., Salamonson, Y., Davidson, Patricia, Parr, M., Hillman, K.
Format: Journal Article
Published: College of Intensive Care Medicine 2010
Online Access:http://hdl.handle.net/20.500.11937/38718
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author Frost, S.
Tam, V.
Alexandrou, Evan
Hunt, L.
Salamonson, Y.
Davidson, Patricia
Parr, M.
Hillman, K.
author_facet Frost, S.
Tam, V.
Alexandrou, Evan
Hunt, L.
Salamonson, Y.
Davidson, Patricia
Parr, M.
Hillman, K.
author_sort Frost, S.
building Curtin Institutional Repository
collection Online Access
description Background: Readmission to intensive care during the same hospital stay has been associated with a greater risk of in-hospital mortality and has been suggested as a marker ofquality of care. There is lack of published research attempting to develop clinical prediction tools that individualise the risk of readmission to the intensive care unit during the same hospital stay. Objective: To develop a prediction model using an inception cohort of patients surviving an initial ICU stay. Design, setting and participants: The study was conducted at Liverpool Hospital, Sydney. An inception cohort of 14 952 patients aged 15 years or more surviving an initial ICU stay and transferred to general wards in the study hospital between 1 January 1997 and 31 December 2007 was used to develop the model. Binary logistic regression was used to develop the prediction model and anomogram was derived to individualise the risk of readmission to the ICU during the same hospital stay. Main outcome measure: Readmission to the ICU during the same hospital stay.Results: Among members of the study cohort there were 987 readmissions to ICU during the study period. Compared with patients not readmitted to the ICU, patients who were readmitted were more likely to have had ICU stays of at least 7 days (odds ratio [OR], 2.2 [95% CI, 1.85-2.56]); non-elective initial admission to the ICU (OR, 1.7[95% CI, 1.44-2.08]); and acute renal failure (OR, 1.6 [95%CI, 0.97-2.47]). Patients admitted to the ICU from the operating theatre or recovery ward had a lower risk of readmission to ICU than those admitted from general wards, the emergency department or other hospitals. The maximum error between observed frequencies and predicted probabilities of readmission to ICU was estimatedto be 3%. The area under the receiver operating characteristic curve of the final model was 0.66.Conclusion: We have developed a practical clinical tool toindividualise the risk of readmission to the ICU during the same hospital stay in patients who survive an initial episodeof intensive care.
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spelling curtin-20.500.11937-387182017-01-30T14:25:09Z Readmission to intensive care: development of a nomogram for individualising risk Frost, S. Tam, V. Alexandrou, Evan Hunt, L. Salamonson, Y. Davidson, Patricia Parr, M. Hillman, K. Background: Readmission to intensive care during the same hospital stay has been associated with a greater risk of in-hospital mortality and has been suggested as a marker ofquality of care. There is lack of published research attempting to develop clinical prediction tools that individualise the risk of readmission to the intensive care unit during the same hospital stay. Objective: To develop a prediction model using an inception cohort of patients surviving an initial ICU stay. Design, setting and participants: The study was conducted at Liverpool Hospital, Sydney. An inception cohort of 14 952 patients aged 15 years or more surviving an initial ICU stay and transferred to general wards in the study hospital between 1 January 1997 and 31 December 2007 was used to develop the model. Binary logistic regression was used to develop the prediction model and anomogram was derived to individualise the risk of readmission to the ICU during the same hospital stay. Main outcome measure: Readmission to the ICU during the same hospital stay.Results: Among members of the study cohort there were 987 readmissions to ICU during the study period. Compared with patients not readmitted to the ICU, patients who were readmitted were more likely to have had ICU stays of at least 7 days (odds ratio [OR], 2.2 [95% CI, 1.85-2.56]); non-elective initial admission to the ICU (OR, 1.7[95% CI, 1.44-2.08]); and acute renal failure (OR, 1.6 [95%CI, 0.97-2.47]). Patients admitted to the ICU from the operating theatre or recovery ward had a lower risk of readmission to ICU than those admitted from general wards, the emergency department or other hospitals. The maximum error between observed frequencies and predicted probabilities of readmission to ICU was estimatedto be 3%. The area under the receiver operating characteristic curve of the final model was 0.66.Conclusion: We have developed a practical clinical tool toindividualise the risk of readmission to the ICU during the same hospital stay in patients who survive an initial episodeof intensive care. 2010 Journal Article http://hdl.handle.net/20.500.11937/38718 College of Intensive Care Medicine fulltext
spellingShingle Frost, S.
Tam, V.
Alexandrou, Evan
Hunt, L.
Salamonson, Y.
Davidson, Patricia
Parr, M.
Hillman, K.
Readmission to intensive care: development of a nomogram for individualising risk
title Readmission to intensive care: development of a nomogram for individualising risk
title_full Readmission to intensive care: development of a nomogram for individualising risk
title_fullStr Readmission to intensive care: development of a nomogram for individualising risk
title_full_unstemmed Readmission to intensive care: development of a nomogram for individualising risk
title_short Readmission to intensive care: development of a nomogram for individualising risk
title_sort readmission to intensive care: development of a nomogram for individualising risk
url http://hdl.handle.net/20.500.11937/38718