Mortality after burn injury in children: A 33-year population-based study

OBJECTIVE: To assess the impact of burn injury sustained during childhood on long-term abstract mortality and to quantify any increased risk of death attributable to burn injury. METHODS: A population-based cohort study of children younger than 15 years hospitalized for burn injury in Western Austra...

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Main Authors: Duke, J., Rea, S., Boyd, James, Randall, S., Wood, F.
Format: Journal Article
Published: American Academy of Pediatrics 2015
Online Access:http://hdl.handle.net/20.500.11937/38653
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author Duke, J.
Rea, S.
Boyd, James
Randall, S.
Wood, F.
author_facet Duke, J.
Rea, S.
Boyd, James
Randall, S.
Wood, F.
author_sort Duke, J.
building Curtin Institutional Repository
collection Online Access
description OBJECTIVE: To assess the impact of burn injury sustained during childhood on long-term abstract mortality and to quantify any increased risk of death attributable to burn injury. METHODS: A population-based cohort study of children younger than 15 years hospitalized for burn injury in Western Australia (1980-2012) and a matched noninjured comparison group. Deidentified extraction of linked hospital morbidity and death records for the period 1980-2012 were provided by the Western Australian Data Linkage System. An inception cohort (1980-2012) of burn cases younger than 15 years of age when hospitalized for a first burn injury (n = 10 426) and a frequency matched noninjured comparison cohort (n = 40 818) were identified. Survival analysis was conducted by using the Kaplan-Meier method and Cox proportional hazards regression. Mortality rate ratios and attributable risk percent adjusted for sociodemographic and preexisting heath factors were generated. RESULTS: The median follow-up time for the pediatric burn cohort was 18.1 years after discharge. The adjusted all-cause mortality rate ratios for burn injury was 1.6 (95% confidence interval: 1.3-2.0); children with burn injury had a 1.6 times greater rate of mortality than those with no injury. The index burn injury was estimated to account for 38% (attributable risk percent) of all recorded deaths in the burn injury cohort during the study period. CONCLUSIONS: Burn injury sustained by children is associated with an increased risk of long-term all-cause mortality. Estimates of the total mortality burden based on in-hospital deaths alone underestimates the true burden from burn injury.
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spelling curtin-20.500.11937-386532017-09-13T14:19:01Z Mortality after burn injury in children: A 33-year population-based study Duke, J. Rea, S. Boyd, James Randall, S. Wood, F. OBJECTIVE: To assess the impact of burn injury sustained during childhood on long-term abstract mortality and to quantify any increased risk of death attributable to burn injury. METHODS: A population-based cohort study of children younger than 15 years hospitalized for burn injury in Western Australia (1980-2012) and a matched noninjured comparison group. Deidentified extraction of linked hospital morbidity and death records for the period 1980-2012 were provided by the Western Australian Data Linkage System. An inception cohort (1980-2012) of burn cases younger than 15 years of age when hospitalized for a first burn injury (n = 10 426) and a frequency matched noninjured comparison cohort (n = 40 818) were identified. Survival analysis was conducted by using the Kaplan-Meier method and Cox proportional hazards regression. Mortality rate ratios and attributable risk percent adjusted for sociodemographic and preexisting heath factors were generated. RESULTS: The median follow-up time for the pediatric burn cohort was 18.1 years after discharge. The adjusted all-cause mortality rate ratios for burn injury was 1.6 (95% confidence interval: 1.3-2.0); children with burn injury had a 1.6 times greater rate of mortality than those with no injury. The index burn injury was estimated to account for 38% (attributable risk percent) of all recorded deaths in the burn injury cohort during the study period. CONCLUSIONS: Burn injury sustained by children is associated with an increased risk of long-term all-cause mortality. Estimates of the total mortality burden based on in-hospital deaths alone underestimates the true burden from burn injury. 2015 Journal Article http://hdl.handle.net/20.500.11937/38653 10.1542/peds.2014-3140 American Academy of Pediatrics unknown
spellingShingle Duke, J.
Rea, S.
Boyd, James
Randall, S.
Wood, F.
Mortality after burn injury in children: A 33-year population-based study
title Mortality after burn injury in children: A 33-year population-based study
title_full Mortality after burn injury in children: A 33-year population-based study
title_fullStr Mortality after burn injury in children: A 33-year population-based study
title_full_unstemmed Mortality after burn injury in children: A 33-year population-based study
title_short Mortality after burn injury in children: A 33-year population-based study
title_sort mortality after burn injury in children: a 33-year population-based study
url http://hdl.handle.net/20.500.11937/38653