Caveolae optimize tissue factor-Factor VIIa inhibitory activity of cell-surface-associated tissue factor pathway inhibitor

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Caveolae optimize tissue factor-Factor VIIa inhibitory activity of cell-surface-associated tissue factor pathway inhibitor

TFPI (tissue factor pathway inhibitor) is an anticoagulant protein that prevents intravascular coagulation through inhibition of fXa (Factor Xa) and the TF (tissue factor)–fVIIa (Factor VIIa) complex. Localization of TFPI within caveolae enhances its anticoagulant activity. To define further how cav...

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Bibliographic Details
Main Authors:	Maroney, S., Ellery, Paul, Wood, J., Ferrel, J., Bonesho, C., Mast, A.
Format:	Journal Article
Published:	2012
Online Access:	http://hdl.handle.net/20.500.11937/38422

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