Prognostic significance of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase protein expression in colorectal cancer patients treated with or without 5-fluorouracil-based chemotherapy

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Prognostic significance of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase protein expression in colorectal cancer patients treated with or without 5-fluorouracil-based chemotherapy

Background: Low tumour expression levels of thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD) and thymidine phosphorylase (TP) have been linked with improved outcome for colorectal cancer (CRC) patients treated with 5-fluorouracil (5-FU). It is unclear whether this occurs because such...

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Bibliographic Details
Main Authors:	Soong, R., Shah, N., Salto-Tellez, M., Tai, B., Soo, R., Han, H., Ng, S., Tan, W., Zeps, Nikolajs, Joseph, D., Diasio, R., Iacopetta, B.
Format:	Journal Article
Published:	Oxford University Press 2008
Online Access:	http://hdl.handle.net/20.500.11937/38030

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