Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection

Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection

HIV-1 subtype C (C-HIV) is responsible for most HIV-1 cases worldwide. Although the pathogenesis of C-HIV is thought to predominantly involve CCR5-restricted (R5) strains, we do not have a firm understanding of how frequently CXCR4-using (X4 and R5X4) variants emerge in subjects with progressive C-H...

Full description

Bibliographic Details
Main Authors: Jakobsen, M., Cashin, K., Roche, M., Sterjovski, J., Ellett, A., Borm, K., Flynn, J., Erikstrup, C., Gouillou, M., Gray, L., Saksena, N., Wang, B., Purcell, D., Kallestrup, P., Zinyama-Gutsire, R., Gomo, E., Ullum, H., Østergaard, L., Lee, B., Ramsland, Paul, Churchill, M., Gorry, P.
Format: Journal Article
Published: 2013
Online Access:http://hdl.handle.net/20.500.11937/37710

Similar Items

Similar Items