Convenient Access to Hydroquinone and Quinone Derivatives from Cyclobutenedione Units

Thirty years ago, cyclobutenediones were only studied as theoretically interesting molecules without much thought towards their potential use in building complex structures.[1–3] Late in the 1980s, these compounds started to find their way into synthetic organic chemistry via their conversion to hig...

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Main Author: Nguyen, Thanh Vinh
Format: Journal Article
Published: CSIRO Publishing 2010
Online Access:http://hdl.handle.net/20.500.11937/37577
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author Nguyen, Thanh Vinh
author_facet Nguyen, Thanh Vinh
author_sort Nguyen, Thanh Vinh
building Curtin Institutional Repository
collection Online Access
description Thirty years ago, cyclobutenediones were only studied as theoretically interesting molecules without much thought towards their potential use in building complex structures.[1–3] Late in the 1980s, these compounds started to find their way into synthetic organic chemistry via their conversion to highly functionalized benzoquinones and cyclopentenones.[1] During the studies of unsaturated ketenes,[4,5] Moore and coworkers discovered one of the most important uses of cyclobutenediones while carrying out the thermolysis of 4-alkynyl-4-hydroxycyclobutenones. These compounds were able to undergo 4p-electrocyclic ring opening to the corresponding enynylketenes, which subsequently ring close to formdiradical intermediates. These intermediates then rearrange to formquinone or hydroquinone derivatives via either radical addition or homolytic substitution, offering a convenient synthetic method to access polycyclic compounds containing quinone/hydroquinone moieties from cyclobutenediones.[4–20]
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publishDate 2010
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spelling curtin-20.500.11937-375772017-09-13T14:01:55Z Convenient Access to Hydroquinone and Quinone Derivatives from Cyclobutenedione Units Nguyen, Thanh Vinh Thirty years ago, cyclobutenediones were only studied as theoretically interesting molecules without much thought towards their potential use in building complex structures.[1–3] Late in the 1980s, these compounds started to find their way into synthetic organic chemistry via their conversion to highly functionalized benzoquinones and cyclopentenones.[1] During the studies of unsaturated ketenes,[4,5] Moore and coworkers discovered one of the most important uses of cyclobutenediones while carrying out the thermolysis of 4-alkynyl-4-hydroxycyclobutenones. These compounds were able to undergo 4p-electrocyclic ring opening to the corresponding enynylketenes, which subsequently ring close to formdiradical intermediates. These intermediates then rearrange to formquinone or hydroquinone derivatives via either radical addition or homolytic substitution, offering a convenient synthetic method to access polycyclic compounds containing quinone/hydroquinone moieties from cyclobutenediones.[4–20] 2010 Journal Article http://hdl.handle.net/20.500.11937/37577 10.1071/CH10189 CSIRO Publishing restricted
spellingShingle Nguyen, Thanh Vinh
Convenient Access to Hydroquinone and Quinone Derivatives from Cyclobutenedione Units
title Convenient Access to Hydroquinone and Quinone Derivatives from Cyclobutenedione Units
title_full Convenient Access to Hydroquinone and Quinone Derivatives from Cyclobutenedione Units
title_fullStr Convenient Access to Hydroquinone and Quinone Derivatives from Cyclobutenedione Units
title_full_unstemmed Convenient Access to Hydroquinone and Quinone Derivatives from Cyclobutenedione Units
title_short Convenient Access to Hydroquinone and Quinone Derivatives from Cyclobutenedione Units
title_sort convenient access to hydroquinone and quinone derivatives from cyclobutenedione units
url http://hdl.handle.net/20.500.11937/37577