A Multiple Model Probability Hypothesis density Tracker for Time-lapse Cell Microscopy Sequences

Quantitative analysis of the dynamics of tiny cellular and subcellular structures in time-lapse cell microscopy sequences requires the development of a reliable multi-target tracking method capable of tracking numerous similar targets in the presence of high levels of noise, high target density, man...

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Main Authors: Rezatofighi, S., Gould, S., Vo, Ba-Ngu, Mele, K., Hughes, W., Hartley, R.
Other Authors: Gee, J.C.
Format: Conference Paper
Published: Springer 2013
Online Access:http://hdl.handle.net/20.500.11937/37288
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author Rezatofighi, S.
Gould, S.
Vo, Ba-Ngu
Mele, K.
Hughes, W.
Hartley, R.
author2 Gee, J.C.
author_facet Gee, J.C.
Rezatofighi, S.
Gould, S.
Vo, Ba-Ngu
Mele, K.
Hughes, W.
Hartley, R.
author_sort Rezatofighi, S.
building Curtin Institutional Repository
collection Online Access
description Quantitative analysis of the dynamics of tiny cellular and subcellular structures in time-lapse cell microscopy sequences requires the development of a reliable multi-target tracking method capable of tracking numerous similar targets in the presence of high levels of noise, high target density, maneuvering motion patterns and intricate interactions. The linear Gaussian jump Markov system probability hypothesis density (LGJMS-PHD) filter is a recent Bayesian tracking filter that is well-suited for this task. However, the existing recursion equations for this filter do not consider a state-dependent transition probability matrix. As required in many biological applications, we propose a new closed-form recursion that incorporates this assumption and introduce a general framework for particle tracking using the proposed filter. We apply our scheme to multi-target tracking in total internal reflection fluorescence microscopy (TIRFM) sequences and evaluate the performance of our filter against the existing LGJMS-PHD and IMM-JPDA filters.
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institution Curtin University Malaysia
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publishDate 2013
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spelling curtin-20.500.11937-372882023-02-13T08:01:34Z A Multiple Model Probability Hypothesis density Tracker for Time-lapse Cell Microscopy Sequences Rezatofighi, S. Gould, S. Vo, Ba-Ngu Mele, K. Hughes, W. Hartley, R. Gee, J.C. Joshi, S. Pohl, K.M. Wells, W.M. Zöllei, L. Quantitative analysis of the dynamics of tiny cellular and subcellular structures in time-lapse cell microscopy sequences requires the development of a reliable multi-target tracking method capable of tracking numerous similar targets in the presence of high levels of noise, high target density, maneuvering motion patterns and intricate interactions. The linear Gaussian jump Markov system probability hypothesis density (LGJMS-PHD) filter is a recent Bayesian tracking filter that is well-suited for this task. However, the existing recursion equations for this filter do not consider a state-dependent transition probability matrix. As required in many biological applications, we propose a new closed-form recursion that incorporates this assumption and introduce a general framework for particle tracking using the proposed filter. We apply our scheme to multi-target tracking in total internal reflection fluorescence microscopy (TIRFM) sequences and evaluate the performance of our filter against the existing LGJMS-PHD and IMM-JPDA filters. 2013 Conference Paper http://hdl.handle.net/20.500.11937/37288 10.1007/978-3-642-38868-2_10 Springer restricted
spellingShingle Rezatofighi, S.
Gould, S.
Vo, Ba-Ngu
Mele, K.
Hughes, W.
Hartley, R.
A Multiple Model Probability Hypothesis density Tracker for Time-lapse Cell Microscopy Sequences
title A Multiple Model Probability Hypothesis density Tracker for Time-lapse Cell Microscopy Sequences
title_full A Multiple Model Probability Hypothesis density Tracker for Time-lapse Cell Microscopy Sequences
title_fullStr A Multiple Model Probability Hypothesis density Tracker for Time-lapse Cell Microscopy Sequences
title_full_unstemmed A Multiple Model Probability Hypothesis density Tracker for Time-lapse Cell Microscopy Sequences
title_short A Multiple Model Probability Hypothesis density Tracker for Time-lapse Cell Microscopy Sequences
title_sort multiple model probability hypothesis density tracker for time-lapse cell microscopy sequences
url http://hdl.handle.net/20.500.11937/37288