PITPs as targets for selectively interfering with phosphoinositide signaling in cells
Sec14-like phosphatidylinositol transfer proteins (PITPs) integrate diverse territories of intracellular lipid metabolism with stimulated phosphatidylinositol-4-phosphate production and are discriminating portals for interrogating phosphoinositide signaling. Yet, neither Sec14-like PITPs nor PITPs i...
| Main Authors: | Nile, A., Tripathi, A., Yuan, P., Mousely, Carl, Suresh, S., Wallace, I., Shah, S., Pohlhaus, D., Temple, B., Nislow, C., Giaever, G., Tropsha, A., Davis, R., St. Onge, R., Bankaitis, V. |
|---|---|
| Format: | Journal Article |
| Published: |
Nature Publishing Group
2014
|
| Online Access: | http://hdl.handle.net/20.500.11937/37090 |
Similar Items
Sec14 like PITPs couple lipid metabolism with phosphoinositide synthesis to regulate golgi functionality
by: Mousley, Carl, et al.
Published: (2015)
by: Mousley, Carl, et al.
Published: (2015)
A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress–induced membrane biogenesis
by: Ren, J., et al.
Published: (2014)
by: Ren, J., et al.
Published: (2014)
Does PITP dependant PtdIns-4-P production promote encystation in
Giardia duodenalis?
by: Davis, Aleesha Jayne
Published: (2020)
by: Davis, Aleesha Jayne
Published: (2020)
Slopes-interfered by man / Cheah Tien Chee
by: Cheah, Tien Chee
Published: (1970)
by: Cheah, Tien Chee
Published: (1970)
Functional Anatomy of Phospholipid Binding and Regulation of Phosphoinositide Homeostasis by Proteins of the Sec14 Superfamily
by: Schaaf, G., et al.
Published: (2008)
by: Schaaf, G., et al.
Published: (2008)
Local control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase
by: Wood, C., et al.
Published: (2012)
by: Wood, C., et al.
Published: (2012)
Class II Phosphoinositide 3-Kinases as Novel Drug Targets
by: Falasca, Marco, et al.
Published: (2017)
by: Falasca, Marco, et al.
Published: (2017)
Genetic and epigenetic regulation of phosphoinositide 3-kinase isoforms
by: Fyffe, C., et al.
Published: (2013)
by: Fyffe, C., et al.
Published: (2013)
Dr M warns of interfering foreign powers, 27 Februari 2012
by: New Sarawak, Tribune
Published: (2012)
by: New Sarawak, Tribune
Published: (2012)
Analysis, regulation, and roles of endosomal phosphoinositides
by: Maffucci, T., et al.
Published: (2014)
by: Maffucci, T., et al.
Published: (2014)
Class II Phosphoinositide 3-Kinases Contribute to Endothelial Cells Morphogenesis
by: Tibolla, G., et al.
Published: (2013)
by: Tibolla, G., et al.
Published: (2013)
Empowered shareholder or interfering shareholder-balancing rights and accountability in governance and decision making
by: Mohd. Sulaiman, Aiman @ Nariman
Published: (2016)
by: Mohd. Sulaiman, Aiman @ Nariman
Published: (2016)
Interfering with the CCL2–glycosaminoglycan axis as a potential approach to modulate neuroinflammation
by: Gschwandtner, Martha, et al.
Published: (2016)
by: Gschwandtner, Martha, et al.
Published: (2016)
Targeting phosphoinositide 3-kinase pathways in pancreatic cancer - from molecular signalling to clinical trials
by: Falasca, Marco, et al.
Published: (2011)
by: Falasca, Marco, et al.
Published: (2011)
3-phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer
by: Fyffe, C., et al.
Published: (2013)
by: Fyffe, C., et al.
Published: (2013)
Key role of phosphoinositide 3-kinase class IB in pancreatic cancer
by: Edling, C., et al.
Published: (2010)
by: Edling, C., et al.
Published: (2010)
Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway
by: Edling, C., et al.
Published: (2014)
by: Edling, C., et al.
Published: (2014)
Regulation and cellular functions of class II phosphoinositide 3-kinases
by: Falasca, Marco, et al.
Published: (2012)
by: Falasca, Marco, et al.
Published: (2012)
Phosphoinositides signalling in cancer: Focus on PI3K and PLC
by: Raimondi, C., et al.
Published: (2012)
by: Raimondi, C., et al.
Published: (2012)
New insight into the intracellular roles of class II phosphoinositide 3-kinases
by: Maffucci, T., et al.
Published: (2014)
by: Maffucci, T., et al.
Published: (2014)
Phosphoinositide 3-kinase pathway inhibitors: pharmacology, metabolism & drug development
by: Falasca, Marco
Published: (2011)
by: Falasca, Marco
Published: (2011)
Elucidation of the WNT & AKT/Phosphoinositide-3-Kinase Pathways in Colorectal Carcinoma
by: Khor, Tin Oo
Published: (2004)
by: Khor, Tin Oo
Published: (2004)
Small interfering RNA silencing of interleukin-6 in mesenchymal stromal cells inhibits multiple myeloma cell growth
by: Teoh, Hoon Koon, et al.
Published: (2016)
by: Teoh, Hoon Koon, et al.
Published: (2016)
Design and validation of small interfering RNA on respiratory syncytial virus M2-2 gene: a potential approach in RNA interference on viral replication
by: Chin, V. K., et al.
Published: (2016)
by: Chin, V. K., et al.
Published: (2016)
THE CLASS II PHOSPHOINOSITIDE 3-KINASE ISOFORM beta REGULATES PLATELET FUNCTION AND ARTERIAL THROMBOSIS IN MICE
by: Tibolla, G., et al.
Published: (2011)
by: Tibolla, G., et al.
Published: (2011)
Class II phosphoinositide 3-kinase C2ß regulates a novel signaling pathway involved in breast cancer progression.
by: Chikh, A., et al.
Published: (2016)
by: Chikh, A., et al.
Published: (2016)
Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic ß cells
by: Dominguez, V., et al.
Published: (2011)
by: Dominguez, V., et al.
Published: (2011)
Golgi membrane dynamics and lipid metabolism
by: Bankaitis, V., et al.
Published: (2012)
by: Bankaitis, V., et al.
Published: (2012)
A sterol-binding protein integrates endosomal lipid metabolism with TOR signaling and nitrogen sensing
by: Mousley, Carl, et al.
Published: (2012)
by: Mousley, Carl, et al.
Published: (2012)
Functional association of phosphoinositide-3-kinase with platelet glycoprotein Iba, the major ligand-binding subunit of the glycoprotein Ib-IX-V complex
by: Mu, F., et al.
Published: (2010)
by: Mu, F., et al.
Published: (2010)
Investigating the mechanisms of activation and action of phosphoinositide 3-kinase C2 alpha in pancreatic beta cells
by: Mazza, S., et al.
Published: (2013)
by: Mazza, S., et al.
Published: (2013)
Cocoa polyphenols treatment ameliorates visceral obesity by reduction lipogenesis and promoting fatty acid oxidation genes in obese rats through interfering with AMPK pathway
by: Ali, Faisal, et al.
Published: (2016)
by: Ali, Faisal, et al.
Published: (2016)
The oxysterol-binding protein superfamily: New concepts and old proteins
by: Villasmil, M., et al.
Published: (2012)
by: Villasmil, M., et al.
Published: (2012)
The Sec14 superfamily and mechanisms for crosstalk between lipid metabolism and lipid signaling
by: Bankaitis, V., et al.
Published: (2010)
by: Bankaitis, V., et al.
Published: (2010)
Incorporation of dietary fibre-rich oyster mushroom (Pleurotus
sajor-caju) powder improves postprandial glycaemic response
by interfering with starch granule structure and starch digestibility
of biscuit
by: Sze, Han Ng, et al.
Published: (2017)
by: Sze, Han Ng, et al.
Published: (2017)
A phosphoinositide 3-kinase/phospholipase cgamma1 pathway regulates fibroblast growth factor-induced capillary tube formation
by: Maffucci, T., et al.
Published: (2009)
by: Maffucci, T., et al.
Published: (2009)
The roles of transportation and transportation hubs in the propagation of influenza and coronaviruses: a systematic review
by: Browne, Annie, et al.
Published: (2016)
by: Browne, Annie, et al.
Published: (2016)
Novel roles for class II Phosphoinositide 3-Kinase C2ß in signalling pathways involved in prostate cancer cell invasion.
by: Mavrommati, I., et al.
Published: (2016)
by: Mavrommati, I., et al.
Published: (2016)
Cudraflavone C induces tumor-specific apoptosis in colorectal cancer cells through inhibition of the phosphoinositide 3-kinase (PI3K)-AKT pathway
by: Castresana, Javier S., et al.
Published: (2017)
by: Castresana, Javier S., et al.
Published: (2017)
All Prizes paid in full
by: Nile, Richard, et al.
Published: (2008)
by: Nile, Richard, et al.
Published: (2008)
Similar Items
-
Sec14 like PITPs couple lipid metabolism with phosphoinositide synthesis to regulate golgi functionality
by: Mousley, Carl, et al.
Published: (2015) -
A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress–induced membrane biogenesis
by: Ren, J., et al.
Published: (2014) -
Does PITP dependant PtdIns-4-P production promote encystation in
Giardia duodenalis?
by: Davis, Aleesha Jayne
Published: (2020) -
Slopes-interfered by man / Cheah Tien Chee
by: Cheah, Tien Chee
Published: (1970) -
Functional Anatomy of Phospholipid Binding and Regulation of Phosphoinositide Homeostasis by Proteins of the Sec14 Superfamily
by: Schaaf, G., et al.
Published: (2008)