Alanyl-glutamine improves pancreatic ß-cell function following ex vivo inflammatory challenge

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Alanyl-glutamine improves pancreatic ß-cell function following ex vivo inflammatory challenge

Obesity-associated diabetes and concomitant inflammation may compromise pancreatic β-cell integrity and function. l-glutamine and l-alanine are potent insulin secretagogues, with antioxidant and cytoprotective properties. Herein, we studied whether the dipeptide l-alanyl-l-glutamine (Ala-Gln) could...

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Bibliographic Details
Main Authors:	Cruzat, Vinicius, Keane, Kevin, Scheinpflug, A., Cordeiro, R., Soares, M., Newsholme, Philip
Format:	Journal Article
Published:	BioScientifica Ltd. 2015
Online Access:	http://hdl.handle.net/20.500.11937/36990

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