Interaction of acridine-calix[4]arene with DNA at the electrified liquid|liquid interface
The behaviour of an acridine-functionalised calix[4]arene at the interface between two immiscible electrolyte solutions (ITIES) is reported. Molecular modelling showed that the acridine-calix[4]arene has regions of significant net positive charge spread throughout the protonated acridine moieties, c...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
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Pergamon-Elsevier Science Ltd
2010
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/36680 |
| _version_ | 1848754837181693952 |
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| author | Kivlehan, F. Lefoix, M. Moynihan, H. Thompson, D. Ogurtsov, V. Herzog, G. Arrigan, Damien |
| author_facet | Kivlehan, F. Lefoix, M. Moynihan, H. Thompson, D. Ogurtsov, V. Herzog, G. Arrigan, Damien |
| author_sort | Kivlehan, F. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The behaviour of an acridine-functionalised calix[4]arene at the interface between two immiscible electrolyte solutions (ITIES) is reported. Molecular modelling showed that the acridine-calix[4]arene has regions of significant net positive charge spread throughout the protonated acridine moieties, consistent with it being able to function as an anion ionophore. The presence of this compound in the organic phase facilitated the transfer of aqueous phase electrolyte ions. Upon addition of double stranded DNA to the aqueous phase, the transfer of electrolyte anions was diminished, due to DNA binding to the acridine moiety at the ITIES. The behaviour provides a basis for DNA hybridization detection using electrochemistry at the ITIES. |
| first_indexed | 2025-11-14T08:46:45Z |
| format | Journal Article |
| id | curtin-20.500.11937-36680 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:46:45Z |
| publishDate | 2010 |
| publisher | Pergamon-Elsevier Science Ltd |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-366802017-09-13T16:07:21Z Interaction of acridine-calix[4]arene with DNA at the electrified liquid|liquid interface Kivlehan, F. Lefoix, M. Moynihan, H. Thompson, D. Ogurtsov, V. Herzog, G. Arrigan, Damien Interface Impedance Calixarene DNA ITIES Voltammetry Acridine The behaviour of an acridine-functionalised calix[4]arene at the interface between two immiscible electrolyte solutions (ITIES) is reported. Molecular modelling showed that the acridine-calix[4]arene has regions of significant net positive charge spread throughout the protonated acridine moieties, consistent with it being able to function as an anion ionophore. The presence of this compound in the organic phase facilitated the transfer of aqueous phase electrolyte ions. Upon addition of double stranded DNA to the aqueous phase, the transfer of electrolyte anions was diminished, due to DNA binding to the acridine moiety at the ITIES. The behaviour provides a basis for DNA hybridization detection using electrochemistry at the ITIES. 2010 Journal Article http://hdl.handle.net/20.500.11937/36680 10.1016/j.electacta.2010.01.042 Pergamon-Elsevier Science Ltd fulltext |
| spellingShingle | Interface Impedance Calixarene DNA ITIES Voltammetry Acridine Kivlehan, F. Lefoix, M. Moynihan, H. Thompson, D. Ogurtsov, V. Herzog, G. Arrigan, Damien Interaction of acridine-calix[4]arene with DNA at the electrified liquid|liquid interface |
| title | Interaction of acridine-calix[4]arene with DNA at the electrified liquid|liquid interface |
| title_full | Interaction of acridine-calix[4]arene with DNA at the electrified liquid|liquid interface |
| title_fullStr | Interaction of acridine-calix[4]arene with DNA at the electrified liquid|liquid interface |
| title_full_unstemmed | Interaction of acridine-calix[4]arene with DNA at the electrified liquid|liquid interface |
| title_short | Interaction of acridine-calix[4]arene with DNA at the electrified liquid|liquid interface |
| title_sort | interaction of acridine-calix[4]arene with dna at the electrified liquid|liquid interface |
| topic | Interface Impedance Calixarene DNA ITIES Voltammetry Acridine |
| url | http://hdl.handle.net/20.500.11937/36680 |